An Agarose–Curdlan Nanogel that Carries Etanercept to Target and Neutralises TNF-α Produced by Dectin-1-Expressing Immune Cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Electronic Materials"
DOI: 10.1007/s11664-019-07458-2
Abstract: Etanercept (ETA) has been used as a drug to neutralise tumour necrotic factor alpha (TNF-α) for treatment of rheumatoid arthritis (RA), yet there are limitations concerning its low specific drug targeting and side effects. In… read more here.
Keywords: curdlan nanogel; tnf produced; agarose curdlan; eta ... See more keywords
Synthesis and characterization of regioselectively substituted curdlan hetero esters with different ester groups on primary and secondary hydroxyl groups.
Sign Up to like & getrecommendations! Published in 2018 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.10.046
Abstract: Two kinds of regioselectively substituted curdlan hetero ester, 2,4-di-O-acetyl-6-O-propionyl-curdlan (CD24Ac6Pr) and 2,4-di-O-propionyl-6-O-acetyl-curdlan (CD24Pr6Ac), were synthesized. By repeating detritylation and esterification, a new method to remove trityl group from 6-O-trityl-curdlan without acyl migration was developed. Their… read more here.
Keywords: curdlan hetero; substituted curdlan; ester; ester groups ... See more keywords
Oxidation pattern of curdlan with TEMPO-mediated system.
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DOI: 10.1016/j.carbpol.2017.12.080
Abstract: In this study, the TEMPO-mediated (TEMPO/NaBr/NaClO) oxidation pattern of curdlan was investigated through comprehensively structural analysis of the corresponding oxidized products. During the structural analysis, infrared spectroscopy (IR), nuclear magnetic resonance (NMR) spectroscopy, gel permeation… read more here.
Keywords: oxidation; spectroscopy; tempo mediated; curdlan ... See more keywords
Polydopamine-coated curdlan hydrogel as a potential carrier of free amino group-containing molecules.
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DOI: 10.1016/j.carbpol.2020.117524
Abstract: Curdlan hydrogel obtained after thermal gelling exhibits elasticity and high water-absorbing capacity. However, its modifications leading to the increase of biofunctionality usually alter its solubility and reduce mechanical parameters. Therefore, curdlan hydrogel was modified by… read more here.
Keywords: curdlan hydrogel; drug; curdlan; polydopamine coated ... See more keywords
Exploiting diol reactivity for the access to unprecedented low molecular weight curdlan sulfate polysaccharides.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118324
Abstract: Curdlan is a bacterial sourced polysaccharide, consisting of a linear backbone of β-1 → 3-linked glucose (Glc) units. The high interest in pharmaceutical applications of curdlan and derivatives thereof is fueling the study of multi-step sequences for… read more here.
Keywords: low molecular; weight curdlan; molecular weight; sulfation ... See more keywords
Use of FT-IR, FT-Raman and thermal analysis to evaluate the gel formation of curdlan produced by Agrobacterium sp. IFO 13140 and determination of its rheological properties with food applicability.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.04.031
Abstract: Curdlan is a linear polysaccharide composed of glucose units joined by β-(1,3) bonds that possesses unique gelation properties. This study aimed to characterize the structure and evaluate the gelling properties of curdlan produced by Agrobacterium… read more here.
Keywords: curdlan produced; produced agrobacterium; ifo 13140; curdlan ... See more keywords
Water-soluble β-1,3-glucan prepared by degradation of curdlan with hydrogen peroxide.
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DOI: 10.1016/j.foodchem.2019.01.036
Abstract: This study aims to prepare water-soluble β-1,3-glucan (WSG) by hydrolysis of curdlan with H2O2. The hydrolysis conditions were optimised as follows: reaction time of 40 min, H2O2 concentration of 2%, temperature of 85 °C and NaOH concentration… read more here.
Keywords: soluble glucan; prepared degradation; water soluble; curdlan ... See more keywords
Recent progress on curdlan provided by functionalization strategies
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DOI: 10.1016/j.foodhyd.2016.09.014
Abstract: Abstract Curdlan, a high molecular weight 1,3-β-D-glucan, is a natural biomaterial that has shown practical applications in food industry as a gelling agent and texture modifier. Simultaneously curdlan and chemically modified curdlan have also shown… read more here.
Keywords: progress curdlan; provided functionalization; curdlan provided; recent progress ... See more keywords
Macromolecular behavior, structural characteristics and rheological properties of alkali-neutralization curdlan at different concentrations
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DOI: 10.1016/j.foodhyd.2020.105785
Abstract: Abstract Curdlan is insoluble in water at ambient temperatures due to its rigid triple helix structure, which greatly limits its applications in the food industry. Alkali-neutralization (AN) treatment is a promising strategy for curdlan dissolution.… read more here.
Keywords: structural characteristics; treatment; rheological properties; characteristics rheological ... See more keywords
Dual-responsive hydrogels based on maleilated curdlan-graft-poly(N-isopropylacrylamide)
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DOI: 10.1080/00914037.2017.1417289
Abstract: ABSTRACT The esterification reaction between curdlan and maleic anhydride was performed to provide polymerizable double bonds and pH-sensitive carboxylic groups for the curdlan chains. The new derivative was used as macromolecular cross-linker in the polymerization… read more here.
Keywords: dual responsive; based maleilated; hydrogels based; maleilated curdlan ... See more keywords
Synthesis and characterization of bioplastic curdlan esters with an introduced flexible carboxylic acid side chain.
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DOI: 10.2139/ssrn.4120104
Abstract: Curdlan, a linear β-1,3-glucan, was reacted with glutaric anhydride and heptanoyl chloride to afford thermoplastic curdlan esters (CrdE(HepGlu)) with a carboxylic acid side chain. CrdE(HepGlu) with a degree of substitution of the glutaric acid monoester… read more here.
Keywords: curdlan; carboxylic acid; crde hepglu; acid side ... See more keywords