Cancer immunotherapy trial design with cure rate and delayed treatment effect.
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DOI: 10.1002/sim.8440
Abstract: Cancer immunotherapy trials have two special features: a delayed treatment effect and a cure rate. Both features violate the proportional hazard model assumption and ignoring either one of the two features in an immunotherapy trial… read more here.
Keywords: delayed treatment; cure rate; trial; design ... See more keywords
Mild sporadic primary hyperparathyroidism: high rate of multiglandular disease is associated with lower surgical cure rate
Sign Up to like & getrecommendations! Published in 2019 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-019-01782-1
Abstract: BackgroundMild primary hyperparathyroidism (serum calcium ≤ 2.85 mmol/L) is the most representative form of pHPT nowadays. The aim of this study was to evaluate its subtypes and the multiglandular disease (MGD) rate as it may lower the… read more here.
Keywords: primary hyperparathyroidism; surgical cure; cure; rate ... See more keywords
Discovery of Small Molecule Therapeutics for Treatment of Chronic HBV Infection.
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DOI: 10.1021/acsinfecdis.7b00144
Abstract: The chronic infection of hepatitis B virus (HBV) inflicts 250 million people worldwide representing a major public health threat. A significant subpopulation of patients eventually develop cirrhosis and hepatocellular carcinoma (HCC). Unfortunately, none of the… read more here.
Keywords: discovery small; treatment; infection; hbv ... See more keywords
A note on the EM algorithm for estimation in the destructive negative binomial cure rate model
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DOI: 10.1080/00949655.2017.1327589
Abstract: ABSTRACT In this note we present a modification in the EM algorithm for the destructive negative binomial cure rate model. This alteration enables us to obtain the estimates of the whole parameter vector from the… read more here.
Keywords: note; destructive negative; rate model; negative binomial ... See more keywords
On bootstrap testing inference in cure rate models
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DOI: 10.1080/00949655.2018.1522316
Abstract: ABSTRACT Survival models deal with the time until the occurrence of an event of interest. However, in some situations the event may not occur in part of the studied population. The fraction of the population… read more here.
Keywords: cure rate; bootstrap testing; testing inference; rate models ... See more keywords
Risk factors influencing cure of ultrasound-guided microwave ablation for primary hyperparathyroidism
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DOI: 10.1080/02656736.2022.2029957
Abstract: Abstract Objective To evaluate the potential risk factors influencing cure rate of ultrasound-guided microwave ablation (MWA) for primary hyperparathyroidism (PHPT). Materials and methods Seventy five patients (25 males and 50 females; mean age, 56.80 ± 12.34; age… read more here.
Keywords: factors influencing; influencing cure; cure rate; risk ... See more keywords
A new cure rate model based on the Yule–Simon distribution with application to a melanoma data set
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DOI: 10.1080/02664763.2016.1194385
Abstract: ABSTRACT In this paper, a new survival cure rate model is introduced considering the Yule–Simon distribution [12] to model the number of concurrent causes. We study some properties of this distribution and the model arising… read more here.
Keywords: simon distribution; model; yule simon; cure rate ... See more keywords
A new semiparametric Weibull cure rate model: fitting different behaviors within GAMLSS
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DOI: 10.1080/02664763.2019.1611748
Abstract: ABSTRACT We propose a new semiparametric Weibull cure rate model for fitting nonlinear effects of explanatory variables on the mean, scale and cure rate parameters. The regression model is based on the generalized additive models… read more here.
Keywords: new semiparametric; model; semiparametric weibull; cure rate ... See more keywords
Stochastic EM algorithm for generalized exponential cure rate model and an empirical study
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DOI: 10.1080/02664763.2020.1786676
Abstract: In this paper, we consider two well-known parametric long-term survival models, namely, the Bernoulli cure rate model and the promotion time (or Poisson) cure rate model. Assuming the long-term survival probability to depend on a… read more here.
Keywords: rate model; model; generalized exponential; cure rate ... See more keywords
A weighted Poisson distribution and its application to cure rate models
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DOI: 10.1080/03610926.2017.1373817
Abstract: ABSTRACT The family of weighted Poisson distributions offers great flexibility in modeling discrete data due to its potential to capture over/under-dispersion by an appropriate selection of the weight function. In this paper, we introduce a… read more here.
Keywords: cure rate; poisson distribution; weighted poisson; distribution ... See more keywords
Cure Rate of Fungal Keratitis With Antibacterial Therapy
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DOI: 10.1097/ico.0000000000001170
Abstract: Purpose: To study the cure rate of fungal keratitis with moxifloxacin 0.3% monotherapy. Methods: A retrospective review of patients with culture-proven fungal keratitis who initially received moxifloxacin 0.3% monotherapy was performed. Results: Eleven patients with… read more here.
Keywords: cure rate; rate fungal; keratitis; fungal keratitis ... See more keywords