Current and emerging approaches to noncompetitive AR inhibition.
Sign Up to like & getrecommendations! Published in 2023 at "Medicinal research reviews"
DOI: 10.1002/med.21961
Abstract: The androgen receptor (AR) has been shown to be a key determinant in the pathogenesis of castration-resistant prostate cancer (CRPC). The current standard of care therapies targets the ligand-binding domain of the receptor and can… read more here.
Keywords: emerging approaches; inhibition; noncompetitive inhibition; approaches noncompetitive ... See more keywords
Current and Emerging Therapies for Acute Myeloid Leukemia.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer treatment and research"
DOI: 10.1007/978-3-030-78311-2_4
Abstract: Acute myeloid leukemia (AML) is predominantly a disease of older adults and the majority of affected patients succumb to the disease. After decades of slow progress, the last 5Â years have witnessed remarkable progress in AML… read more here.
Keywords: myeloid leukemia; current emerging; acute myeloid; emerging therapies ... See more keywords
Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-018-1264-1
Abstract: Atherosclerotic plaques can remain quiescent for years, but become life threatening upon rupture or disruption, initiating clot formation in the vessel lumen and causing acute myocardial infarction and ischemic stroke. Whether and how a plaque… read more here.
Keywords: approaches imaging; high risk; current emerging; emerging preclinical ... See more keywords
Current and Emerging Therapeutic Targets for Metastatic Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Current Oncology Reports"
DOI: 10.1007/s11912-018-0684-z
Abstract: Purpose of reviewThe treatment of advanced renal cell carcinoma has evolved dramatically over recent years. In this review, we will summarize current and emerging therapies based on molecular targets and provide insight into treatment strategy… read more here.
Keywords: cell carcinoma; renal cell; treatment; current emerging ... See more keywords
Cyclodestructive Procedures in Glaucoma: A Review of Current and Emerging Options
Sign Up to like & getrecommendations! Published in 2018 at "Advances in Therapy"
DOI: 10.1007/s12325-018-0837-3
Abstract: The first surgical modalities to reduce aqueous humor production by damaging the ciliary body date back to the early twentieth century. Until recently, however, cyclodestructive procedures (e.g., cyclocryotherapy and transscleral diode laser photocoagulation) have been… read more here.
Keywords: current emerging; procedures glaucoma; cyclodestructive procedures; glaucoma ... See more keywords
Current and Emerging Options for the Management of Inherited von Willebrand Disease
Sign Up to like & getrecommendations! Published in 2017 at "Drugs"
DOI: 10.1007/s40265-017-0793-2
Abstract: Von Willebrand disease (VWD) is the most common inherited bleeding disorder with an estimated prevalence of ~1% and clinically relevant bleeding symptoms in approximately 1:10,000 individuals. VWD is caused by a deficiency and/or defect of… read more here.
Keywords: current emerging; management; von willebrand; therapy ... See more keywords
Current and emerging strategies for management of myelodysplastic syndromes.
Sign Up to like & getrecommendations! Published in 2020 at "Blood reviews"
DOI: 10.1016/j.blre.2020.100791
Abstract: Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis with varying degrees of dysplasia and peripheral cytopenias. MDS are driven by structural chromosomal alterations and somatic mutations in neoplastic myeloid cells, which are supported by a… read more here.
Keywords: strategies management; myelodysplastic syndromes; management myelodysplastic; emerging strategies ... See more keywords
Current emerging SARS-CoV-2 pandemic: Potential direct/indirect negative impacts of virus persistence and related therapeutic drugs on the aquatic compartments
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Research"
DOI: 10.1016/j.envres.2020.109808
Abstract: Abstract The purpose of the present work is to provide a complete overview of possible direct/indirect implications on the quality of aquatic compartments due to the recent SARS-CoV-2 outbreak. With this aim, the environmental impacts… read more here.
Keywords: persistence; direct indirect; current emerging; aquatic compartments ... See more keywords
Current and emerging treatment strategies for hair loss in women of color☆
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Women's Dermatology"
DOI: 10.1016/j.ijwd.2018.10.021
Abstract: Hair loss is common in women of color, and is associated with significant psychosocial complaints. Early clinical recognition and prompt initiation of intervention with medical treatment is critical to halt the disease process. In this… read more here.
Keywords: emerging treatment; women color; hair loss; current emerging ... See more keywords
Part 2. Current and emerging treatments for hidradenitis suppurativa.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2019.08.089
Abstract: Treatment of hidradenitis suppurativa (HS) has remained challenging due to the many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of HS have enabled the investigation of newer therapies. The second article in… read more here.
Keywords: treatments hidradenitis; current emerging; hidradenitis suppurativa; emerging treatments ... See more keywords
Current and emerging pharmacological options for the treatment of nonalcoholic steatohepatitis.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2020.154203
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent disease and important unmet medical need. Current guidelines recommend, under specific restrictions, pioglitazone or vitamin E in patients with NASH and significant fibrosis, but the use… read more here.
Keywords: nonalcoholic steatohepatitis; current emerging; treatment; receptor ... See more keywords