Current and Emerging Therapeutic Targets for Essential Tremor: A Critical Appraisal of Recent Preclinical and Clinical Studies
Sign Up to like & getrecommendations! Published in 2025 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.70147
Abstract: Essential tremor (ET) is a common hyperkinetic movement disorder and causes significant disability. However, the response to the commonly used medications is often unsatisfactory. Hence, there is a requirement for improved treatment modalities involving novel… read more here.
Keywords: therapeutic targets; targets essential; essential tremor; emerging therapeutic ... See more keywords
Current and emerging approaches to noncompetitive AR inhibition.
Sign Up to like & getrecommendations! Published in 2023 at "Medicinal research reviews"
DOI: 10.1002/med.21961
Abstract: The androgen receptor (AR) has been shown to be a key determinant in the pathogenesis of castration-resistant prostate cancer (CRPC). The current standard of care therapies targets the ligand-binding domain of the receptor and can… read more here.
Keywords: emerging approaches; inhibition; noncompetitive inhibition; approaches noncompetitive ... See more keywords
Current emerging therapeutic targets and clinical investigational agents for schizophrenia: Challenges and opportunities
Sign Up to like & getrecommendations! Published in 2024 at "Medicinal Research Reviews"
DOI: 10.1002/med.22086
Abstract: Since the first discovery of antipsychotics in the 1950s, targeting dopaminergic drugs has manifested to well manage the positive symptoms of schizophrenia with limited efficacy for the negative and cognitive symptoms. In past decades, extensive… read more here.
Keywords: therapeutic targets; investigational agents; targets clinical; clinical investigational ... See more keywords
Current and Emerging Therapies for Acute Myeloid Leukemia.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer treatment and research"
DOI: 10.1007/978-3-030-78311-2_4
Abstract: Acute myeloid leukemia (AML) is predominantly a disease of older adults and the majority of affected patients succumb to the disease. After decades of slow progress, the last 5 years have witnessed remarkable progress in AML… read more here.
Keywords: myeloid leukemia; current emerging; acute myeloid; emerging therapies ... See more keywords
Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-018-1264-1
Abstract: Atherosclerotic plaques can remain quiescent for years, but become life threatening upon rupture or disruption, initiating clot formation in the vessel lumen and causing acute myocardial infarction and ischemic stroke. Whether and how a plaque… read more here.
Keywords: approaches imaging; high risk; current emerging; emerging preclinical ... See more keywords
Current and Emerging Therapeutic Targets for Metastatic Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Current Oncology Reports"
DOI: 10.1007/s11912-018-0684-z
Abstract: Purpose of reviewThe treatment of advanced renal cell carcinoma has evolved dramatically over recent years. In this review, we will summarize current and emerging therapies based on molecular targets and provide insight into treatment strategy… read more here.
Keywords: cell carcinoma; renal cell; treatment; current emerging ... See more keywords
Advanced Electroanatomic Mapping: Current and Emerging Approaches
Sign Up to like & getrecommendations! Published in 2024 at "Current treatment options in cardiovascular medicine"
DOI: 10.1007/s11936-024-01034-6
Abstract: Contemporary ablation for complex arrhythmias raises several challenges for electroanatomic mapping. We examine how current and emerging systems may meet these challenges, and we outline major unmet needs. The latest versions of the 3 major… read more here.
Keywords: mapping current; advanced electroanatomic; emerging approaches; mapping ... See more keywords
Cyclodestructive Procedures in Glaucoma: A Review of Current and Emerging Options
Sign Up to like & getrecommendations! Published in 2018 at "Advances in Therapy"
DOI: 10.1007/s12325-018-0837-3
Abstract: The first surgical modalities to reduce aqueous humor production by damaging the ciliary body date back to the early twentieth century. Until recently, however, cyclodestructive procedures (e.g., cyclocryotherapy and transscleral diode laser photocoagulation) have been… read more here.
Keywords: current emerging; procedures glaucoma; cyclodestructive procedures; glaucoma ... See more keywords
Current and Emerging Options for the Management of Inherited von Willebrand Disease
Sign Up to like & getrecommendations! Published in 2017 at "Drugs"
DOI: 10.1007/s40265-017-0793-2
Abstract: Von Willebrand disease (VWD) is the most common inherited bleeding disorder with an estimated prevalence of ~1% and clinically relevant bleeding symptoms in approximately 1:10,000 individuals. VWD is caused by a deficiency and/or defect of… read more here.
Keywords: current emerging; management; von willebrand; therapy ... See more keywords
Current and emerging strategies for management of myelodysplastic syndromes.
Sign Up to like & getrecommendations! Published in 2020 at "Blood reviews"
DOI: 10.1016/j.blre.2020.100791
Abstract: Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis with varying degrees of dysplasia and peripheral cytopenias. MDS are driven by structural chromosomal alterations and somatic mutations in neoplastic myeloid cells, which are supported by a… read more here.
Keywords: strategies management; myelodysplastic syndromes; management myelodysplastic; emerging strategies ... See more keywords
Current emerging SARS-CoV-2 pandemic: Potential direct/indirect negative impacts of virus persistence and related therapeutic drugs on the aquatic compartments
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Research"
DOI: 10.1016/j.envres.2020.109808
Abstract: Abstract The purpose of the present work is to provide a complete overview of possible direct/indirect implications on the quality of aquatic compartments due to the recent SARS-CoV-2 outbreak. With this aim, the environmental impacts… read more here.
Keywords: persistence; direct indirect; current emerging; aquatic compartments ... See more keywords