Inhibition of Late Sodium Current as an Innovative Antiarrhythmic Strategy
Sign Up to like & getrecommendations! Published in 2017 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-017-0333-0
Abstract: Purpose of reviewOver the last years, evidence is accumulating that enhanced late sodium current (INaL) in cardiac pathologies has fundamental consequences for cellular electrophysiology. This review discusses the underlying mechanisms of INaL-induced arrhythmias and the… read more here.
Keywords: late sodium; sodium current; heart failure; current innovative ... See more keywords
Current and innovative emerging therapies for porphyrias with hepatic involvement.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2019.05.003
Abstract: Porphyrias are rare inherited disorders caused by specific enzyme dysfunctions in the haem synthesis pathway, which result in abnormal accumulation of specific pathway intermediates. The symptoms depend upon the chemical characteristics of these substances. Porphyrins… read more here.
Keywords: porphyrias hepatic; innovative emerging; current innovative; emerging therapies ... See more keywords