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Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.589680
Abstract: Although many approaches have been used to treat hepatocellular carcinoma (HCC), the clinical benefits remain limited, particularly for late stage HCC. In recent years, studies have focused on immunotherapy for HCC. Immunotherapies have shown promising…
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Keywords:
hepatocellular carcinoma;
carcinoma;
immunotherapy hepatocellular;
limits prospects ... See more keywords
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Published in 2018 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2017-0303
Abstract: Beyond finding inhibitors that show high binding affinity to the respective target, there is the challenge of optimizing their properties with respect to metabolic and toxicological issues, as well as further off-target effects. To reduce…
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Keywords:
virtual screening;
property prediction;
limits virtual;
screening property ... See more keywords