Mechanisms of Uptake and Membrane Curvature Generation for the Internalization of Silica Nanoparticles by Cells
Sign Up to like & getrecommendations! Published in 2022 at "Nano Letters"
DOI: 10.1021/acs.nanolett.2c00537
Abstract: Nanosized drug carriers enter cells via active mechanisms of endocytosis but the pathways involved are often not clarified. Cells possess several mechanisms to generate membrane curvature during uptake. However, the mechanisms of membrane curvature generation… read more here.
Keywords: silica nanoparticles; curvature generation; generation internalization; membrane curvature ... See more keywords
Modelling membrane curvature generation using mechanics and machine learning
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2022.0448
Abstract: The deformation of cellular membranes regulates trafficking processes, such as exocytosis and endocytosis. Classically, the Helfrich continuum model is used to characterize the forces and mechanical parameters that cells tune to accomplish membrane shape changes.… read more here.
Keywords: mechanical parameters; machine learning; curvature generation; model ... See more keywords