Improvement of Curvulamine Production by Precursors Co-addition Strategy in Liquid Culture of Marine-Derived Fungus Curvularia sp. IFB-Z10
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DOI: 10.1007/s12010-019-03072-4
Abstract: Curvulamine, a novel scaffold alkaloid with remarkable selective antibacterial activity, is produced by marine fungus Curvularia sp. IFB-Z10. However, its deep pharmaceutical research and application are severely restricted by the low yield, which needs to… read more here.
Keywords: curvulamine production; curvulamine; precursors addition; ifb z10 ... See more keywords
Total Synthesis of (-)-Curvulamine.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b12546
Abstract: Curvulamine and related polypyrrole alkaloids represent a fascinating new class of natural products with unprecedented chemical structures, intriguing biological activities, and mysterious biosynthetic origins. Herein we report the first studies towards these molecules, resulting in… read more here.
Keywords: total synthesis; synthesis curvulamine; curvulamine;