Extracellular vesicle‐mediated delivery of circDYM alleviates CUS‐induced depressive‐like behaviours
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12185
Abstract: Abstract Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and severely limits psychosocial function and quality of life, but no effective medication is currently available. Circular RNAs (circRNAs) have been revealed to… read more here.
Keywords: circdym; rvg circdym; circdym evs; cus induced ... See more keywords
Legumain acts on neuroinflammatory to affect CUS-induced cognitive impairment
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2019.112219
Abstract: Cognitive impairment has been widely recognized as a central feature of depression. Legumain, a lysosomal cysteine protease, plays an important role in cancer, atherosclerosis, inflammation and other pathological conditions. Meanwhile, it has been reported that… read more here.
Keywords: legumain; cognitive impairment; cus induced; induced cognitive ... See more keywords
Chronic unpredictable stress-induced reproductive deficits were prevented by probiotics.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive biology"
DOI: 10.1016/j.repbio.2020.03.005
Abstract: Stress can induce reproductive deficits by activating the HPA and causing oxidative stress. Some studies have indicated that the neurologic diseases or disorders induced by stress could be relieved by probiotics. Whether chronic unpredictable stress… read more here.
Keywords: lgg; reproductive deficits; cus induced; stress ... See more keywords
Ouabain Reverts CUS-Induced Disruption of the HPA Axis and Avoids Long-Term Spatial Memory Deficits
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041177
Abstract: Ouabain (OUA) is a cardiotonic steroid that modulates Na+, K+ -ATPase activity. OUA has been identified as an endogenous substance that is present in human plasma, and it has been shown to be associated with… read more here.
Keywords: long term; term spatial; memory; cus ... See more keywords