Articles with "cusatuzumab" as a keyword



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Cusatuzumab plus azacitidine in Japanese patients with newly diagnosed acute myeloid leukemia ineligible for intensive treatment

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Published in 2022 at "Cancer Science"

DOI: 10.1111/cas.15663

Abstract: We present the results of a phase 1 study that evaluated the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary disease response to cusatuzumab, a novel anti‐CD70 monoclonal antibody, in combination with azacitidine, in newly diagnosed acute… read more here.

Keywords: myeloid leukemia; newly diagnosed; acute myeloid; diagnosed acute ... See more keywords
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Results from a phase I/II trial of cusatuzumab combined with azacitidine in patients with newly diagnosed acute myeloid leukemia who are ineligible for intensive chemotherapy.

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Published in 2023 at "Haematologica"

DOI: 10.3324/haematol.2022.281563

Abstract: Cusatuzumab is a high-affinity, anti-CD70 monoclonal antibody under investigation in AML. This two-part, open-label, multicenter, phase I/II trial evaluated cusatuzumab plus azacitidine in patients with newly diagnosed AML ineligible for intensive chemotherapy. Patients received a… read more here.

Keywords: patients newly; newly diagnosed; phase trial; azacitidine patients ... See more keywords