CCN3 secreted by prostaglandin E2 inhibits intimal cushion formation in the rat ductus arteriosus.
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DOI: 10.1016/j.bbrc.2018.08.138
Abstract: The ductus arteriosus (DA), an essential fetal shunt between the pulmonary trunk and the descending aorta, changes its structure during development. Our previous studies have demonstrated that prostaglandin E2 (PGE2)-EP4 signaling promotes intimal cushion formation… read more here.
Keywords: cushion formation; pge2; ccn3 secreted; smooth muscle ... See more keywords