Customized Reversible Stapling for Selective Delivery of Bioactive Peptides.
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DOI: 10.1021/jacs.2c10949
Abstract: We have developed a new concept for reversible peptide stapling that involves macrocyclization between two amino groups and decyclization promoted via dual 1,4-elimination. Depending on the trigger moiety, this strategy could be employed to selectively… read more here.
Keywords: selective delivery; reversible stapling; customized reversible; peptide ... See more keywords