Predicting physiologically-relevant oxygen concentrations in precision-cut liver slices using mathematical modelling
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DOI: 10.1371/journal.pone.0275788
Abstract: Precision cut liver slices represent an encouraging ex vivo method to understand the pathogenesis of liver disease alongside drug induced liver injury. Despite being more physiologically relevant compared to in vitro models, precision cut liver… read more here.
Keywords: precision cut; liver slices; oxygen; cut liver ... See more keywords
Improved Precision-Cut Liver Slice Cultures for Testing Drug-Induced Liver Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.862185
Abstract: In vitro models of human liver disease often fail to mimic the complex 3D structures and cellular organizations found in vivo. Precision cut liver slices (PCLS) retain the complex physiological architecture of the native liver… read more here.
Keywords: cut liver; pcls; pcls cultures; fibrosis ... See more keywords