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   Articles with "cut tag" as a keyword



Untargeted CUT&Tag reads are enriched at accessible chromatin and restrict identification of potential G4-forming sequences in G4-targeted CUT&Tag experiments

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recommendations! Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf678

Abstract: Abstract G-quadruplex DNA structures (G4s) form within single-stranded DNA in nucleosome-free chromatin. G4s modulate gene expression and genomic stability, so high-throughput, genome-wide mapping of G4s has generated strong research interest and methodological innovation. Recently, the… read more here.

Keywords: targeted cut; cut tag; g4s; untargeted cut ... See more keywords

Abstract 871: Accurate estimation of open chromatin and intrinsic biases in bulk and single-cell CUT&Tag data

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-871

Abstract: Histone modifications (HM) and transcription factors (TF) are aberrantly regulated in the pathogenesis of humans and are a major class of cancer cell dependencies. Precise detection of HM and TF binding genome-wide is essential for… read more here.

Keywords: cut tag; single cell; tag data; cut ... See more keywords

Abstract 7023: Application of exclusive liquid repellency for low input CUT&Tag histone analyses in prostate cancer spheroids

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recommendations! Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-7023

Abstract: Introduction/Background: Epigenetic alterations, including histone modifications and DNA methylation, drive treatment resistance and lethal prostate cancer. However, epigenetic assays typically require thousands of cells and are difficult to scale for patient tumor biopsies. While identifying… read more here.

Keywords: cancer; cut tag; prostate cancer; culture ... See more keywords

Abstract A057: Microscale analysis of histone modifications in rare cell populations in prostate cancer

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.prca2023-a057

Abstract: Pre-clinical models have identified diverse epigenetic alterations in prostate cancer that associate with treatment resistance and may also be therapeutic targets. However, these assays typically require thousands of cells and are difficult to scale for… read more here.

Keywords: cell; prostate cancer; histone; cut tag ... See more keywords