Incidence of Cutaneous Adverse Events With Phosphoinositide 3-Kinase Inhibitors as Adjuvant Therapy in Patients With Cancer: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.4327
Abstract: Importance The phosphoinositide 3-kinase (PI3K) pathway is among the most frequently activated pathways in human cancers. As the use of PI3K inhibitors for cancer treatment grows, there is increasing need for understanding the cutaneous effects… read more here.
Keywords: incidence cutaneous; incidence; pi3k inhibitors; analysis ... See more keywords
Cutaneous adverse drug reaction in a dog following firocoxib treatment
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.541
Abstract: Abstract A 9‐year‐old intact female toy poodle was presented with oedema around the neck, including pus and cutaneous necrosis, 2 days after starting firocoxib treatment and placement of a cervical collar for intervertebral disc disease.… read more here.
Keywords: treatment; cutaneous adverse; firocoxib treatment; adverse drug ... See more keywords
Twelve cases of acneiform eruptions while on anti-CTLA4 therapy
Sign Up to like & getrecommendations! Published in 2020 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-020-05381-5
Abstract: We present the first detailed report of acneiform eruptions in patients on CTLA-4 inhibitor therapy. Acneiform eruptions commonly occur (up to 75–100%) as a cutaneous adverse event associated with EGFR inhibition; however, acneiform eruptions have… read more here.
Keywords: ctla inhibitor; inhibitor therapy; acneiform eruptions; cutaneous adverse ... See more keywords
The 10th International Congress on Cutaneous Adverse Drug Reactions, Shimane, Japan, 2018: Focus on New Discoveries
Sign Up to like & getrecommendations! Published in 2019 at "Drug Safety"
DOI: 10.1007/s40264-019-00818-1
Abstract: The first International Congress on Cutaneous Adverse Drug Reactions took place in Paris, France, in 1994. Latterly, the 10th International Congress on Cutaneous Adverse Drug Reactions was held at the Shimane Civic Center in Shimane,… read more here.
Keywords: congress; drug reactions; meeting; cutaneous adverse ... See more keywords
The oncological survival and prognosis of individuals receiving PD-1 inhibitor with and without immunologic cutaneous adverse events.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2019.06.035
Abstract: BACKGROUND The treatment response to new immunotherapy in advanced melanoma patients remains varied between individuals. Immune related cutaneous side effects may have prognostic value. OBJECTIVE To determine whether developing one or more of the three… read more here.
Keywords: prognosis individuals; cutaneous adverse; least one; adverse events ... See more keywords
Cutaneous Adverse Events Caused by Sulfonamide-Containing Drugs: Reality or Perception?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01932
Abstract: The term "sulfa allergy", originally coined for the sulfonamide antibiotics, has become associated with any drugs that contain a sulfonamide moiety. This raises a question: should medicinal chemists avoid making sulfonamide-containing compounds in drug discovery… read more here.
Keywords: caused sulfonamide; events caused; perception; cutaneous adverse ... See more keywords
Factors inducing cutaneous adverse reactions in cancer patients treated with PD-1 and PD-L1 inhibitors: a machine-learning algorithm approach
Sign Up to like & getrecommendations! Published in 2024 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2024.2430670
Abstract: Abstract Background Immune checkpoint inhibitors (ICIs) show promise in cancer treatment but can lead to immune-related adverse events (irAEs), notably affecting the skin. Understanding the factors behind these skin reactions is crucial for effective management… read more here.
Keywords: cancer; treatment; adverse reactions; adverse events ... See more keywords
A retrospective single-centre case series of paediatric blistering severe cutaneous adverse reactions (SCARs): evaluation using new diagnostic classification confirms value of British Association of Dermatologists' guidelines.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llad014
Abstract: Stevens-Johnson syndrome and toxic epidermonecrolysis are especially challenging to diagnose and manage in paediatric population given their rarity, more frequent infectious triggers and lack of randomized controlled trials to guide management. This retrospective case series… read more here.
Keywords: case series; paediatric blistering; series paediatric; cutaneous adverse ... See more keywords
Severe cutaneous adverse drug reaction to atovaquone/proguanil.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of travel medicine"
DOI: 10.1093/jtm/taae145
Abstract: Atovaquone/proguanil is frequently prescribed among travellers to malaria-endemic areas. Side effects most commonly include headaches and gastrointestinal symptoms. Nevertheless, physicians should be aware of possible rare severe cutaneous adverse reactions, in order to facilitate the… read more here.
Keywords: atovaquone proguanil; drug; cutaneous adverse; severe cutaneous ... See more keywords
Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines and Cutaneous Adverse Reactions: A Review
Sign Up to like & getrecommendations! Published in 2021 at "Dermatitis"
DOI: 10.1097/der.0000000000000755
Abstract: We are entering a new stage of the severe acute respiratory syndrome coronavirus 2 pandemic with the initiation of large-scale vaccination programs globally. In these circumstances, even rare adverse effects of vaccines may be encountered… read more here.
Keywords: cutaneous adverse; syndrome coronavirus; acute respiratory; respiratory syndrome ... See more keywords
A Decadal Exploration of Cutaneous Adverse Effects of FDA-Approved Cardiovascular Medications: Insights From 2013 to 2023
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001660
Abstract: Abstract: Given the high prevalence of cardiovascular disease in the United States, there is a critical need for new medications to improve the outcomes of these diseases. The US Food and Drug Administration has approved… read more here.
Keywords: exploration cutaneous; cutaneous adverse; cardiovascular medications; 2013 2023 ... See more keywords