Management of Cutaneous Immune-Related Adverse Events in Patients With Cancer Treated With Immune Checkpoint Inhibitors: A Systematic Review.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2021.4318
Abstract: Importance There exists a paucity of literature that summarizes the effective management of cutaneous immune-related adverse events (cirAEs) in patients with cancer who are receiving immune checkpoint inhibitors (ICIs). Most published articles are small case… read more here.
Keywords: patients cancer; cutaneous immune; management cutaneous; review ... See more keywords
Low grade cutaneous immune related adverse events leading to immunotherapy discontinuation.
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DOI: 10.1093/ced/llad180
Abstract: Cutaneous immune related adverse events (cirAEs) are a common toxicity due to immune checkpoint inhibitors (ICI) to treat cancer. We provide a case series of 10 patients who presented with low severity cirAEs who had… read more here.
Keywords: cutaneous immune; immune related; related adverse; low grade ... See more keywords
Cutaneous immune‐related adverse events in patients with melanoma treated with checkpoint inhibitors
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DOI: 10.1111/bjd.19750
Abstract: Checkpoint inhibitor (CPI) therapy has vastly improved long‐term outcomes in metastatic malignant melanoma (MMM). Therapy takes the form of monoclonal antibody infusions that target immune cell checkpoint proteins, such as cytotoxic T‐lymphocyte‐associated protein 4 (CTLA4)… read more here.
Keywords: immune related; cutaneous iraes; cutaneous immune; checkpoint ... See more keywords
Checkpoint inhibitor‐associated bullous cutaneous immune‐related adverse events: a multicentre observational study *
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DOI: 10.1111/bjd.21836
Abstract: Checkpoint inhibitor (CPI) therapy has significantly improved overall survival in several cancers including metastatic melanoma (MM) and in the adjuvant setting. Cutaneous immune‐related adverse events (irAEs) secondary to CPIs are commonly observed; however, autoimmune blistering… read more here.
Keywords: checkpoint inhibitor; cutaneous immune; immune related; related adverse ... See more keywords
Cutaneous immune‐related adverse events and photodamaged skin in patients with metastatic melanoma: could nicotinamide be useful?
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DOI: 10.1111/ced.15215
Abstract: Cutaneous immune‐related adverse events (irAEs) occur in more than one‐third of patients treated with immune checkpoint inhibitors; they are often the first clinical manifestation, although they may occur months after initiation of therapy. We noticed… read more here.
Keywords: cutaneous immune; photodamaged skin; immune related; related adverse ... See more keywords
IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in the Absence of the Wiskott–Aldrich Syndrome Protein
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DOI: 10.3389/fimmu.2022.817427
Abstract: Wiskott–Aldrich Syndrome (WAS) is characterized by recurrent infections, thrombocytopenia, and eczema. Here, we show that WASp-deficient mice on a BALB/c background have dysregulated cutaneous immune homeostasis with increased leukocyte accumulation in the skin, 1 week… read more here.
Keywords: aldrich syndrome; cutaneous immune; immune homeostasis; dysregulated cutaneous ... See more keywords