Utility of a Noninvasive 2-Gene Molecular Assay for Cutaneous Melanoma and Effect on the Decision to Biopsy
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2017.0473
Abstract: Importance Expression of long intergenic non–protein coding RNA 518 (LINC00518) and preferentially expressed antigen in melanoma (PRAME) genes, obtained via noninvasive adhesive patch biopsy, is a sensitive and specific method for detection of cutaneous melanoma.… read more here.
Keywords: biopsy; utility; pla; cutaneous melanoma ... See more keywords
Lifetime Sunburn Trajectories and Associated Risks of Cutaneous Melanoma and Squamous Cell Carcinoma Among a Cohort of Norwegian Women.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4053
Abstract: Importance To our knowledge, no study has prospectively investigated sunburn patterns over age periods from childhood to adulthood and their associations with skin cancer risk. Objective To identify lifetime trajectories of sunburns and compare the… read more here.
Keywords: cell carcinoma; cscc; squamous cell; melanoma squamous ... See more keywords
Association Between Metastatic Melanoma Response to Checkpoint Inhibitor Therapy and Tumor-Infiltrating Lymphocyte Classification on Primary Cutaneous Melanoma Biopsies.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4959
Abstract: This cohort study examines the association between tumor-infiltrating lymphocyte classification and disease progression among patients with metastatic primary cutaneous melanoma receiving checkpoint inhibitor therapy. read more here.
Keywords: tumor infiltrating; melanoma; primary cutaneous; cutaneous melanoma ... See more keywords
Development and Validation of a Modified Pathologic Nodal Classification System for Cutaneous Melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA surgery"
DOI: 10.1001/jamasurg.2021.4298
Abstract: Importance Given the evolving patterns of lymph node evaluation for cutaneous melanoma, it is unclear whether the current nodal classification system will continue to accurately reflect prognosis in the modern era. Existing nodal staging for… read more here.
Keywords: classification; system; cutaneous melanoma; lymph node ... See more keywords
Attitudes of patients with cutaneous melanoma toward prognostic testing using the 31‐gene expression profile test
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DOI: 10.1002/cam4.5047
Abstract: Although most patients diagnosed with early‐stage cutaneous melanoma (CM) have excellent outcomes, because of the large number diagnosed each year, many will experience recurrence or death. Prognostic testing for CM using the 31‐gene expression profile… read more here.
Keywords: expression profile; gene expression; prognostic testing; testing using ... See more keywords
Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival
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DOI: 10.1002/ijc.31243
Abstract: Cutaneous melanoma (CM) is considered as a steroid hormone‐related malignancy. However, few studies have evaluated the roles of genetic variants encoding steroid hormone receptor genes and their related regulators (SHR‐related genes) in CM‐specific survival (CMSS).… read more here.
Keywords: dnmt1 associated; genetic variants; cutaneous melanoma; risk genotypes ... See more keywords
Kinesin family member 18B: A contributor and facilitator in the proliferation and metastasis of cutaneous melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22409
Abstract: Melanoma is the most aggressive type of cutaneous tumor and the occurrence of metastasis makes it resistant to almost all available treatment and becomes incorrigible. Hence, identifying metastasis‐related biomarkers and effective therapeutic targets will assist… read more here.
Keywords: melanoma; family member; proliferation; metastasis ... See more keywords
Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
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DOI: 10.1002/jso.25319
Abstract: New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk‐stratified surveillance. Robust predictive markers might permit optimization of agent to… read more here.
Keywords: risk; identification risk; cutaneous melanoma; predictive markers ... See more keywords
Identification of immune-related genes with prognostic significance in the microenvironment of cutaneous melanoma
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DOI: 10.1007/s00428-020-02948-9
Abstract: Cutaneous melanoma is one of the most aggressive cancers characterized by increasing incidence and mortality. In recent years, the emergence of immunotherapy has greatly raised the survival rate of patients suffering from cutaneous melanoma, yet… read more here.
Keywords: melanoma; microenvironment; immune related; cutaneous melanoma ... See more keywords
Polymorphisms in apoptosis-related genes in cutaneous melanoma prognosis: sex disparity
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DOI: 10.1007/s12032-016-0868-z
Abstract: Cutaneous melanoma (CM) cells are resistant to apoptosis, and steroid hormones are involved in this process through regulation of TP53, MDM2, BAX, and BCL2 expression. We analyzed herein sex differences in outcomes of CM patients… read more here.
Keywords: melanoma; tp53 mdm2; cutaneous melanoma; sex ... See more keywords
Assessing beauticians’ knowledge of cutaneous melanoma and willingness to contribute to melanoma surveillance practices on the general population☆☆☆
Sign Up to like & getrecommendations! Published in 2020 at "Anais Brasileiros de Dermatologia"
DOI: 10.1016/j.abd.2020.03.016
Abstract: Melanoma it is the most aggressive skin cancer, with a high mortality rate. Delayed diagnosis contributes to the poor prognosis. Early detection is the best approach to improve the outcome in melanoma patients. Approximately 50%… read more here.
Keywords: melanoma; surveillance practices; detection; cutaneous melanoma ... See more keywords