Unexpected UVR and non-UVR mutation burden in some acral and cutaneous melanomas
Sign Up to like & getrecommendations! Published in 2017 at "Laboratory Investigation"
DOI: 10.1038/labinvest.2016.143
Abstract: Ultraviolet radiation (UVR) mutagenesis causes nearly all cutaneous melanomas, however, since UVR signatures are largely absent in acral melanoma, as well as melanoma in sun-protected sites, the cause of these melanomas is unknown. Whole-genome sequencing… read more here.
Keywords: melanomas; non uvr; mutation burden; cutaneous melanomas ... See more keywords
Genetic profile of naïve untreated primary cutaneous melanomas with a negative sentinel lymph node
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.14321
Abstract: Sentinel lymph node (SLN) biopsy is typically offered to patients with primary cutaneous melanomas (PCMs) of ≥ 1 mm depth, but not all SLNs are positive using this cutoff. To ascertain whether positivity is genetically… read more here.
Keywords: group; primary cutaneous; sentinel lymph; lymph node ... See more keywords
Comparison of phenotypic features in patients with single vs multiple primary cutaneous melanomas: a prospective single‐center study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Dermatology"
DOI: 10.1111/ijd.16432
Abstract: There is sparse data regarding total body nevus count (TBNC), nevus count in specific locations, phenotypic factors, anthropometric indices, sunburn, and the relation to multiple primary cutaneous melanomas (MPCM) development. We aim to compare these… read more here.
Keywords: primary cutaneous; phenotypic features; cutaneous melanomas; multiple primary ... See more keywords
The impact of the COVID‐19 pandemic on the diagnosis of cutaneous melanomas: A retrospective cohort study from five European skin cancer reference centres
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18953
Abstract: The COVID‐19 lockdown had a dramatic impact on primary care access and resulted in postponed skin cancer screenings. This raises concerns for a diagnostic delay on primary cutaneous melanomas, which can subsequently increase morbidity and… read more here.
Keywords: cutaneous melanomas; covid pandemic; skin cancer; impact covid ... See more keywords
Four-color fluorescence in-situ hybridization is useful to assist to distinguish early stage acral and cutaneous melanomas from dysplastic junctional or compound nevus
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic Pathology"
DOI: 10.1186/s13000-020-00937-9
Abstract: Background/objective Acral and cutaneous melanomas are usually difficult to accurately diagnose in the early stage, owing to the similarity in clinical manifestations and morphology with those of dysplastic nevus (DN). In this study, we aimed… read more here.
Keywords: color; early stage; acral cutaneous; four color ... See more keywords
Cutaneous Melanomas: A Single Center Experience on the Usage of Immunohistochemistry Applied for the Diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23115911
Abstract: Cutaneous melanoma (cM) is the deadliest of all primary skin cancers. Its prognosis is strongly influenced by the stage at diagnosis, with early stages having a good prognosis and being potentially treatable with surgery alone;… read more here.
Keywords: melanomas single; single center; center experience; diagnosis ... See more keywords