Cux2 expression regulated by Lhx2 in the upper layer neurons of the developing cortex.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.004
Abstract: The laminar structure, a unique feature of the mammalian cerebrum, is formed by a number of genes in a highly complex process. The pyramidal neurons that make up each layer of the cerebrum are functionally… read more here.
Keywords: expression regulated; layer neurons; cortical layer; expression ... See more keywords
Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21611-7
Abstract: Atrial fibrillation (AF) is the most common arrhythmia. In 2014, two new meta-GWAS identified 5 AF loci, including the NEURL locus, GJA1 locus, CAND2 locus, and TBX5 locus in the European ancestry populations and the… read more here.
Keywords: atrial fibrillation; neurl gja1; gja1; cux2 ... See more keywords
CUX2/KDM5B/SOX17 axis affects the occurrence and development of breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac110
Abstract: OBJECTIVE Abnormal expression of CUT-like homeobox 2 gene (CUX2) has been highlighted as potential clinical biomarkers in human cancers. Notably, the function of CUX2 has been less elucidated in breast cancer (BC). We focused on… read more here.
Keywords: cux2 kdm5b; kdm5b sox17; sox17 axis; expression ... See more keywords