Two Sides of the Same Coin: Pediatric-Onset and Adult-Onset Common Variable Immune Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0415-5
Abstract: PurposeCommon variable immunodeficiency (CVID) is a complex, heterogeneous immunodeficiency characterized by hypogammaglobulinemia, recurrent infections, and poor antibody response to vaccination. While antibiotics and immunoglobulin prophylaxis have significantly reduced infectious complications, non-infectious complications of autoimmunity, inflammatory… read more here.
Keywords: cvid patients; adult onset; adult; pediatric onset ... See more keywords
Responses to SARS-CoV-2 Vaccines of Patients with Common Variable Immune Deficiencies and X-linked Agammaglobulinemia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-022-01251-3
Abstract: We read with great interest the article by Ane F Salinas et al. [1] concerning early immune responses after BNT162b2 immunization in a cohort of 41 SARS-CoV-2 infectionnaïve or previously infected patients with common variable… read more here.
Keywords: previously infected; mrna 1273; sars cov; previously uninfected ... See more keywords
Autoimmune diseases associated with common variable immune deficiency
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13339
Abstract: Common variable immunodeficiency (CVID) is the most prevalent primary immune deficiency, affecting roughly 2‐4/100 000 individuals in the general population. The etiology is currently unknown, even if several genetic mutations have been described, and no… read more here.
Keywords: cvid patients; autoimmune; immune deficiency; common variable ... See more keywords
Common variable immunodeficiency patients display elevated plasma levels of granulocyte activation markers elastase and myeloperoxidase
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738419843381
Abstract: Common variable immunodeficiency disorders (CVIDs) represent a group of primary immunodeficiency diseases characterized by hypogammaglobulinemia and dysfunctional immune response to invading pathogens. Previous studies have indicated that CVID is associated with microbial translocation and systemic… read more here.
Keywords: cvid patients; granulocyte activation; elastase myeloperoxidase; activation markers ... See more keywords
Altered Microbiota, Impaired Quality of Life, Malabsorption, Infection, and Inflammation in CVID Patients With Diarrhoea
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DOI: 10.3389/fimmu.2020.01654
Abstract: Background: Diarrhoea is the commonest gastrointestinal symptom in patients with common variable immunodeficiency (CVID). Objective: The aim of this study was to describe the prevalence and clinical presentation of chronic and recurrent diarrhoea in the… read more here.
Keywords: cvid patients; diversity; diarrhoea; patients diarrhoea ... See more keywords
The Immune Response to SARS-CoV-2 Vaccination: Insights Learned From Adult Patients With Common Variable Immune Deficiency
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.815404
Abstract: CVID patients have an increased susceptibility to vaccine-preventable infections. The question on the potential benefits of immunization of CVID patients against SARS-CoV-2 offered the possibility to analyze the defective mechanisms of immune responses to a… read more here.
Keywords: cvid patients; immunization; spike; immune response ... See more keywords
Liver Stiffness by Transient Elastography Correlates With Degree of Portal Hypertension in Common Variable Immunodeficiency Patients With Nodular Regenerative Hyperplasia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.864550
Abstract: Nodular regenerative hyperplasia (NRH) is associated with high morbidity and mortality in patients with common variable immunodeficiency (CVID). While liver biopsy is the gold standard for NRH diagnosis, a non-invasive technique could facilitate early disease… read more here.
Keywords: cvid patients; liver; disease; liver stiffness ... See more keywords
B- and T-Cell Subset Abnormalities in Monogenic Common Variable Immunodeficiency
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912826
Abstract: Common variable immunodeficiency (CVID) is a heterogeneous group of inborn errors of immunity characterized by reduced serum concentrations of different immunoglobulin isotypes. CVID is the most prevalent symptomatic antibody deficiency with a broad range of… read more here.
Keywords: cvid patients; cell; variable immunodeficiency; common variable ... See more keywords
Liver disease accompanied by enteropathy in common variable immunodeficiency: Common pathophysiological mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.933463
Abstract: Common variable immunodeficiency (CVID) is one of the inborn errors of immunity that have the greatest clinical impact. Rates of morbidity and mortality are higher in patients with CVID who develop liver disease than in… read more here.
Keywords: cvid patients; common variable; disease; variable immunodeficiency ... See more keywords
A beacon in the dark: COVID-19 course in CVID patients from two European countries: Different approaches, similar outcomes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1093385
Abstract: Background CVID patients present an increased risk of prolonged SARS-CoV-2 infection and re-infection and a higher COVID-19-related morbidity and mortality compared to the general population. Since 2021, different therapeutic and prophylactic strategies have been employed… read more here.
Keywords: cvid patients; treatment; cov infection; sars cov ... See more keywords