Decreased phototoxicity of photodynamic therapy by Cx32/Cx26‐composed GJIC: A “Good Samaritan” effect
Sign Up to like & getrecommendations! Published in 2019 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23044
Abstract: Photodynamic therapy (PDT) has been widely used to treat malignant tumors. Our previous studies indicated that connexin (Cx) 32‐ and Cx26‐composed gap junctional intercellular communication (GJIC) could improve the phototoxicity of PDT. However, the role… read more here.
Keywords: cx26 composed; photodynamic therapy; cx32 cx26; cx26 ... See more keywords
Cx26 keratitis ichthyosis deafness syndrome mutations trigger alternative splicing of Cx26 to prevent expression and cause toxicity in vitro
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DOI: 10.1098/rsos.191128
Abstract: The Cx26 mRNA has not been reported to undergo alternative splicing. In expressing a series of human keratitis ichthyosis deafness (KID) syndrome mutations of Cx26 (A88V, N14K and A40V), we found the production of a… read more here.
Keywords: splice; syndrome mutations; cx26; kid syndrome ... See more keywords
Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release
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DOI: 10.3389/fncel.2021.819194
Abstract: GJB2 and GJB6 are adjacent genes encoding connexin 26 (Cx26) and connexin 30 (Cx30), respectively, with overlapping expressions in the inner ear. Both genes are associated with the commonest monogenic hearing disorder, recessive isolated deafness… read more here.
Keywords: hearing loss; cx26; mice; cx30 ... See more keywords
The Expression of Connexin 26 Regulates the Radiosensitivity of Hepatocellular Carcinoma Cells through a Mitogen-Activated Protein Kinases Signal Pathway
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DOI: 10.3390/ijms232314644
Abstract: Connexin 26 (Cx26) is a protein that constitutes a gap junction and is widely expressed in the liver. Abnormal expression of Cx26 is one of the important mechanisms of liver cancer, and is closely related… read more here.
Keywords: hepatocellular carcinoma; liver cancer; radiosensitivity hepatocellular; expression ... See more keywords