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   Articles with "cx3cl1" as a keyword



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Total saponins of panax ginseng via the CX3CL1/CX3CR1 axis attenuates neuroinflammation and exerted antidepressant‐like effects in chronic unpredictable mild stress in rats

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recommendations! Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7696

Abstract: Total saponins of Panax ginseng (TSPG) have antidepressant effects. However, the underlying antidepressant mechanism of TSPG remains not clear. This study aimed to predict the mechanism of TSPG by bioinformatics analysis and to verify it… read more here.

Keywords: total saponins; cx3cl1 cx3cr1; cx3cl1; saponins panax ... See more keywords
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Role of MSK1 in the Induction of NF-κB by the Chemokine CX3CL1 in Microglial Cells

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recommendations! Published in 2019 at "Cellular and Molecular Neurobiology"

DOI: 10.1007/s10571-019-00664-w

Abstract: Microglial cells are essential mediators of neuroinflammatory processes involved in several pathologies. Moreover, the chemokine fractalkine (CX3CL1) is essential in the crosstalk between neurons and microglia. However, the exact roles of CX3CL1, CX3CL1 receptor (CX3CR1)… read more here.

Keywords: msk1 induction; cx3cl1; microglial cells; pro inflammatory ... See more keywords
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Impaired Autophagy in the Fibroblasts by Titanium Particles Increased the Release of CX3CL1 and Promoted the Chemotactic Migration of Monocytes

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recommendations! Published in 2019 at "Inflammation"

DOI: 10.1007/s10753-019-01149-0

Abstract: Aseptic loosening (AL) is the most frequent cause of failure of total hip arthroplasties (THA). Prosthetic wear particle-induced monocyte recruitment to the periprosthetic tissue and subsequent inflammatory response are thought to be the major contribution… read more here.

Keywords: release cx3cl1; promoted chemotactic; cx3cl1; chemotactic migration ... See more keywords
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Increased levels of inflammatory biomarker CX3CL1 in patients with chronic obstructive pulmonary disease.

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recommendations! Published in 2019 at "Cytokine"

DOI: 10.1016/j.cyto.2019.154881

Abstract: OBJECTIVE To investigate the concentration of CX3CL1 in serum of patients with chronic obstructive pulmonary disease (COPD), and to evaluate the associations between the CX3CL1 level and systemic inflammation, small airway obstruction, and COPD assessment… read more here.

Keywords: chronic obstructive; cx3cl1; obstructive pulmonary; copd ... See more keywords
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Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus

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recommendations! Published in 2017 at "Mucosal Immunology"

DOI: 10.1038/mi.2017.63

Abstract: CX3CL1 has been implicated in allergen-induced airway CD4+ T-lymphocyte recruitment in asthma. As epidemiological evidence supports a viral infection–allergen synergy in asthma exacerbations, we postulated that rhinovirus (RV) infection in the presence of allergen augments… read more here.

Keywords: proteases cleave; cx3cl1; cx3cl1 shedding; allergenic proteases ... See more keywords
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Elevated Plasma Fractalkine Level Is Associated with the Severity of Hemorrhagic Fever with Renal Syndrome in Humans.

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recommendations! Published in 2021 at "Viral immunology"

DOI: 10.1089/vim.2020.0244

Abstract: Hantaan virus infection may cause severe lethal hemorrhagic fever with renal syndrome (HFRS) in humans. The chemokine fractalkine (CX3CL1) acts as a proinflammatory cytokine, and it is elevated in several infectious diseases. However, little is… read more here.

Keywords: renal syndrome; hemorrhagic fever; cx3cl1; fever renal ... See more keywords
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Shear Stress Counteracts Endothelial CX3CL1 Induction and Monocytic Cell Adhesion

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recommendations! Published in 2017 at "Mediators of Inflammation"

DOI: 10.1155/2017/1515389

Abstract: Flow conditions critically regulate endothelial cell functions in the vasculature. Reduced shear stress resulting from disturbed blood flow can drive the development of vascular inflammatory lesions. On endothelial cells, the transmembrane chemokine CX3CL1/fractalkine promotes vascular… read more here.

Keywords: cx3cl1; shear stress; adhesion; stress ... See more keywords
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Blockage of CX3CL1 Attenuates Platelet and Leukocyte Recruitment in Murine Hepatic I/R

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recommendations! Published in 2022 at "European Surgical Research"

DOI: 10.1159/000524024

Abstract: Introduction The chemokine fractalkine (CX3CL1) is critically involved in the pathophysiology of different inflammatory diseases and myocardial ischemia-reperfusion (I/R). This study aimed to analyze the role of CX3CL1 in the activation of platelets and leukocytes… read more here.

Keywords: perfusion failure; leukocyte recruitment; platelet leukocyte; cx3cl1 ... See more keywords
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Fractalkine induces angiogenic potential in CX3CR1‐expressing monocytes

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recommendations! Published in 2018 at "Journal of Leukocyte Biology"

DOI: 10.1189/jlb.1a0117-002rr

Abstract: We report the unique role of CX3CL1 (or fractalkine) on CD11b+ myelomonocytic cells expressing CX3CR1, the only known receptor for CX3CL1, in promoting blood perfusion recovery. In a mouse ischemic hind‐limb model, CD11b+CX3CR1+ cells migrated… read more here.

Keywords: cd11b cx3cr1; cx3cr1 monocytes; cx3cl1; angiogenic potential ... See more keywords
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SUN-051 Increased Circulating Cytokines in African American Women with Obesity and Elevated HbA1c

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recommendations! Published in 2019 at "Journal of the Endocrine Society"

DOI: 10.1210/js.2019-sun-051

Abstract: Abstract Background: The leading cause of death in US women is cardiovascular disease (CVD). Obesity and type-2 diabetes (T2D) are independent risk factors for cardiovascular disease while obesity is the leading risk factor for T2D.… read more here.

Keywords: american women; african american; obesity; cx3cl1 ... See more keywords
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Laminar shear stress alleviates monocyte adhesion and atherosclerosis development via miR-29b-3p/CX3CL1 axis regulation

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recommendations! Published in 2022 at "Journal of Cell Science"

DOI: 10.1242/jcs.259696

Abstract: ABSTRACT Laminar shear stress (Lss) is an important anti-atherosclerosis (anti-AS) factor, but its mechanism network is not clear. Therefore, this study aimed to identify how Lss acts against AS formation from a new perspective. In… read more here.

Keywords: mir 29b; cx3cl1 axis; cx3cl1; 29b cx3cl1 ... See more keywords