The homozygous CX3CR1-M280 mutation impairs human monocyte survival.
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DOI: 10.1172/jci.insight.95417
Abstract: Several reports have demonstrated that mouse Cx3cr1 signaling promotes monocyte/macrophage survival. In agreement, we previously found that, in a mouse model of systemic candidiasis, genetic deficiency of Cx3cr1 resulted in increased mortality and impaired tissue… read more here.
Keywords: m280; cx3cr1 m280; human monocyte; cx3cr1 ... See more keywords