Involvement of NF-κB and the CX3CR1 Signaling Network in Mechanical Allodynia Induced by Tetanic Sciatic Stimulation
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DOI: 10.1007/s12264-017-0149-7
Abstract: Tetanic stimulation of the sciatic nerve (TSS) triggers long-term potentiation in the dorsal horn of the spinal cord and long-lasting pain hypersensitivity. CX3CL1–CX3CR1 signaling is an important pathway in neuronal–microglial activation. Nuclear factor κB (NF-κB)… read more here.
Keywords: cx3cr1 signaling; cx3cr1; allodynia induced; involvement cx3cr1 ... See more keywords
Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina
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DOI: 10.1038/srep43067
Abstract: Retinitis pigmentosa (RP) encompasses a group of retinal diseases resulting in photoreceptor loss and blindness. We have previously shown in the rd10 mouse model of RP, that rd10 microglia drive degeneration of viable neurons. Norgestrel,… read more here.
Keywords: fractalkine; cx3cr1 signaling; fractalkine cx3cr1; photoreceptor ... See more keywords