CXCL10 encoding synNotch T cells enhance anti-tumor immune responses without systemic side effect.
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DOI: 10.1016/j.bbrc.2020.11.002
Abstract: Modifying T cells to attack tumors using engineered chimeric receptors display powerful new therapeutic capabilities. Unfortunately, the effectiveness of therapeutic T cells is limited due to the inherent T cell responses: certain facets of endogenous… read more here.
Keywords: cxcl10 encoding; anti tumor; synnotch cells; synnotch ... See more keywords