Articles with "cxcl11" as a keyword



RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B.

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Published in 2022 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2022.113139

Abstract: BACKGROUND Breast cancer is the most common malignancy in women populations. METHODS RAMP2-AS1 and CXCL11 expression in breast cancer tissues and cells were determined using RT-qPCR or Western blot. RIP analysis confirmed the interaction between… read more here.

Keywords: cxcl11; breast cancer; ramp2 as1;

Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis

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Published in 2018 at "International Journal of Obesity"

DOI: 10.1038/s41366-018-0102-5

Abstract: Background/Aims:Impaired angiogenesis is linked to adipose tissue (AT) dysfunction, inflammation, and insulin resistance in human obesity. Chemokine (C-X-C motif) receptor. (CXCR3) ligands are important regulators of angiogenesis in different disease contexts such as cancer; however,… read more here.

Keywords: cxcr3; morbidly obese; cxcl11; angiogenesis ... See more keywords

Gut microbial metabolite butyrate suppresses hepatocellular carcinoma growth via CXCL11-dependent enhancement of natural killer cell infiltration

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Published in 2025 at "Gut Microbes"

DOI: 10.1080/19490976.2025.2519706

Abstract: ABSTRACT Gut microbiota-derived butyrate plays a vital role in attenuating hepatocellular carcinoma (HCC) in murine models. However, the precise molecular mechanisms by which butyrate exerts its effects are largely undefined. Plasma short-chain fatty acids (SCFAs)… read more here.

Keywords: cxcl11; cell; tumor; cell infiltration ... See more keywords

CXCL11 expressing C57BL/6 mice have intact adaptive immune responses to viral infection.

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Published in 2022 at "Immunology and cell biology"

DOI: 10.1111/imcb.12541

Abstract: The chemokine receptor CXCR3 is expressed on immune cells to co-ordinate lymphocyte activation and migration. CXCR3 binds three chemokine ligands, CXCL9, CXCL10, and CXCL11. These ligands display distinct expression patterns and ligand signaling biases; however,… read more here.

Keywords: viral infection; cxcl11; cxcl11 expressing; c57bl mice ... See more keywords
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AB0089 SILDENAFIL COUNTERACTS THE ACTIVATION OF CXCR3/CXCL10, -11 AXIS IN SCLERODERMA FIBROBLASTS EXPOSED TO REACTIVE OXYGEN SPECIES

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Published in 2021 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2021-eular.459

Abstract: Oxidative stress associated with vascular damage represents one the major contributor in the pathogenesis of systemic sclerosis (SSc) [1]. Indeed, different studies demonstrated that excessive free radicals production can contribute to the activation of fibrotic… read more here.

Keywords: cxcl10; reactive oxygen; oxygen species; cxcl11 ... See more keywords
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CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases–associated interstitial lung disease and interstitial pneumonia with autoimmune features

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0241719

Abstract: Introduction Interstitial lung disease (ILD) is a heterogeneous group of diseases characterized by varying degrees of lung inflammation and/or fibrosis. We investigated biomarkers to infer whether patients with collagen vascular diseases associated ILD (CVD–ILD) and… read more here.

Keywords: cxcl11; cvd ild; levels cxcl9; cxcl10 cxcl11 ... See more keywords

Immune molecule diagnostics in colorectal cancer: CCL2 and CXCL11

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Published in 2025 at "Open Life Sciences"

DOI: 10.1515/biol-2025-1147

Abstract: Abstract Traditional serrated adenomas (TSAs) and sessile serrated adenomas (SSAs) are known precursors to colorectal cancer (CRC), but differentiating between them morphologically can be challenging. This study developed an immune molecule-based model to distinguish TSA… read more here.

Keywords: colorectal cancer; immune molecule; cxcl11; ccl2 cxcl11 ... See more keywords

CXCL11 Correlates with Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.951247

Abstract: Background Immunotherapy has achieved great success in cancer. Nevertheless, many patients cannot benefit from immune checkpoint blockade therapy because of the scantiness of CD8+ T cell infiltration in the tumor microenvironment (TME). CXCL11 is known… read more here.

Keywords: infiltration; immunotherapy; cxcl11; expression ... See more keywords