Nicotine Suppresses the Invasiveness of Human Trophoblasts by Downregulation of CXCL12 Expression through the Alpha-7 Subunit of the Nicotinic Acetylcholine Receptor
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-019-00095-4
Abstract: Smoke exposure during pregnancy has detrimental effects upon numerous fetal and neonatal outcomes. Nicotine (the main component of tobacco) has been suggested to affect placental development. During placental development, efficient invasion by trophoblasts is required… read more here.
Keywords: invasion; trophoblast invasion; cxcl12 expression; nicotinic acetylcholine ... See more keywords
Reply to ‘Comment on ‘A meta-analysis of CXCL12 expression for cancer prognosis”
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DOI: 10.1038/bjc.2017.445
Abstract: Literature searching concerns. Dr Zu-Bing Mei et al (2018) identify two studies that they claim are not included in our analysis despite meeting the inclusion criteria. Furthermore, they indicate that had these articles been included,… read more here.
Keywords: cancer; analysis; cxcl12 expression; meta analysis ... See more keywords
BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells
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DOI: 10.18632/oncotarget.14398
Abstract: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive, Schwann cell-derived neoplasms of the peripheral nervous system that have recently been shown to possess an autocrine CXCL12/CXCR4 signaling loop that promotes tumor cell proliferation and survival.… read more here.
Keywords: malignant peripheral; peripheral nerve; cxcl12 expression; bh3 mimetics ... See more keywords
Specific overexpression of SIRT1 in mesenchymal stem cells rescues hematopoiesis niche in BMI1 knockout mice through promoting CXCL12 expression
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DOI: 10.7150/ijbs.63876
Abstract: Osteoblastic lineage cells (OBCs) are bone-building cells and essential component of hematopoietic niche, but mechanisms whereby bone-building and hematopoiesis-supportive activities of OBCs could be regulated simultaneously remain largely unknown. Here we found that B cell-specific… read more here.
Keywords: cxcl12 expression; bone; bmi1 mice; niche ... See more keywords