CXCL13 is an activity marker for systemic, but not cutaneous lupus erythematosus: a longitudinal cohort study
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-018-1836-6
Abstract: Serum levels of the IFN-regulated cytokine CXCL13 have been found to correlate with SLEDAI and renal involvement in systemic lupus erythematosus. This study investigates whether CXCL13 can also be a marker of disease activity in… read more here.
Keywords: ccle; disease activity; cxcl13 levels; cxcl13 ... See more keywords
Transcriptome analysis reveals the clinical significance of CXCL13 in Pan-Gyn tumors
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-024-05619-3
Abstract: Gynecologic and breast tumors (Pan-Gyn) exhibit similar characteristics, and the role of CXCL13 in anti-tumor immunity and it’s potential as a biomarker for immune checkpoint blockade (ICB) therapy have been gradually revealed. However, the precise… read more here.
Keywords: tumor; cxcl13; pan gyn; cxcl13 pan ... See more keywords
CXCL13: a common target for immune-mediated inflammatory diseases
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-024-01508-8
Abstract: CXCL13 is a chemokine that plays an important role in the regulation and development of secondary lymphoid organs. CXCL13 is also involved in the regulation of pathological processes, particularly inflammatory responses, of many diseases. The… read more here.
Keywords: immune mediated; common target; cxcl13; mediated inflammatory ... See more keywords
CXCL13 Is Involved in the Lipopolysaccharide-Induced Hyperpermeability of Umbilical Vein Endothelial Cells
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01253-6
Abstract: Sepsis is a disease that is characterized by a severe systemic inflammatory response to microbial infection and lipopolysaccharide (LPS) and is a well-known inducer of sepsis, as well as endothelial cell hyperpermeability. In the present… read more here.
Keywords: sepsis; hyperpermeability; vein endothelial; umbilical vein ... See more keywords
CXCL13 as a Biomarker of Complex Common Variable Immunodeficiency
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-025-01963-2
Abstract: Common Variable Immunodeficiency (CVID) is a group of heterogeneous disorders with common denominators of impaired antibody production and function, and recurrent infections. Currently, prognostic biomarkers for CVID are limited. CXCL13 is a critical regulator of… read more here.
Keywords: common variable; cxcl13; levels cxcl13; variable immunodeficiency ... See more keywords
Up-regulation of chemokine CXCL13 in systemic candidiasis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.11.015
Abstract: Candida albicans is the leading cause of healthcare associated bloodstream infections. Chemokine CXCL13 is well-known involved in inflammation, but its role in candidemia has not been assessed. Our study firstly demonstrated that serum CXCL13 levels… read more here.
Keywords: cxcl13 systemic; pathology; chemokine cxcl13; regulation chemokine ... See more keywords
Analysis of changes in the chemokine CXC ligand 13 in serum and cerebrospinal fluid of patients with neuromyelitis optica
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-85650-7
Abstract: To determine correlation between the Extended Disability Status Scale(EDSS) grade and the progression of neuromyelitis optica(NMO) patients’ levels of the chemokine CXC ligand 13 (CXCL13) in their serum and cerebrospinal fluid. This research included forty-one… read more here.
Keywords: serum cerebrospinal; cerebrospinal fluid; group; cxcl13 ... See more keywords
Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2105822118
Abstract: Significance Our study provides detailed functional and spatial characteristics of immune cells in the LR-CHL microenvironment at single-cell resolution. We describe detailed T cell subset definitions and importantly identified a unique CD4+PD-1+CXCL13+CXCR5− TFH-like subset that… read more here.
Keywords: single cell; cxcr5; chl; biology ... See more keywords
Altered Expression of CXCL13 and Its Chemokine Receptor CXCR5 on B Lymphocytes during Active Graves’ Orbitopathy
Sign Up to like & getrecommendations! Published in 2020 at "Current Eye Research"
DOI: 10.1080/02713683.2020.1786132
Abstract: ABSTRACT Purpose To characterize the phenotypic abnormalities of peripheral B cells in patients with Graves’ orbitopathy (GO) and explore the role of chemokine CXC ligand 13 and its receptor type 5 (CXCL13/CXCR5) in relation to… read more here.
Keywords: cxcr5; graves orbitopathy; expression; receptor ... See more keywords
103 Expression of CXCL13 in Reed Sternberg Cells of Classic Hodgkin Lymphoma (CHL): A Diagnostic Dilemma
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqaf121.232
Abstract: CXCL13 is used to diagnose nodal T-cell lymphomas with follicular helper phenotype (PTCL-TFH). Hodgkin Reed Sternberg cells (HRS) cells can be seen in PTCL-TFH, leading to a difficult diagnosis. We incidentally discovered a lymphoma with… read more here.
Keywords: reed sternberg; ptcl tfh; hrs cells; cxcl13 ... See more keywords
Study on correlation between CXCL13 and prognosis and immune characteristics of ovarian cancer
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000040272
Abstract: Ovarian cancer (OC) has a limited immunotherapeutic response; hence, this study aimed to investigate the relationship between CXC-chemokine ligand 13 (CXCL13) expression and overall survival (OS) rate, key immune pathways, degree of immune cell infiltration,… read more here.
Keywords: cancer; study; ovarian cancer; cxcl13 ... See more keywords