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   Articles with "cxcl13" as a keyword



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CXCL13 is an activity marker for systemic, but not cutaneous lupus erythematosus: a longitudinal cohort study

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recommendations! Published in 2018 at "Archives of Dermatological Research"

DOI: 10.1007/s00403-018-1836-6

Abstract: Serum levels of the IFN-regulated cytokine CXCL13 have been found to correlate with SLEDAI and renal involvement in systemic lupus erythematosus. This study investigates whether CXCL13 can also be a marker of disease activity in… read more here.

Keywords: ccle; disease activity; cxcl13 levels; cxcl13 ... See more keywords
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CXCL13 Is Involved in the Lipopolysaccharide-Induced Hyperpermeability of Umbilical Vein Endothelial Cells

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recommendations! Published in 2020 at "Inflammation"

DOI: 10.1007/s10753-020-01253-6

Abstract: Sepsis is a disease that is characterized by a severe systemic inflammatory response to microbial infection and lipopolysaccharide (LPS) and is a well-known inducer of sepsis, as well as endothelial cell hyperpermeability. In the present… read more here.

Keywords: sepsis; hyperpermeability; vein endothelial; umbilical vein ... See more keywords
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Up-regulation of chemokine CXCL13 in systemic candidiasis.

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recommendations! Published in 2018 at "Clinical immunology"

DOI: 10.1016/j.clim.2017.11.015

Abstract: Candida albicans is the leading cause of healthcare associated bloodstream infections. Chemokine CXCL13 is well-known involved in inflammation, but its role in candidemia has not been assessed. Our study firstly demonstrated that serum CXCL13 levels… read more here.

Keywords: cxcl13 systemic; pathology; chemokine cxcl13; regulation chemokine ... See more keywords
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Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma

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recommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2105822118

Abstract: Significance Our study provides detailed functional and spatial characteristics of immune cells in the LR-CHL microenvironment at single-cell resolution. We describe detailed T cell subset definitions and importantly identified a unique CD4+PD-1+CXCL13+CXCR5− TFH-like subset that… read more here.

Keywords: single cell; cxcr5; chl; biology ... See more keywords
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Altered Expression of CXCL13 and Its Chemokine Receptor CXCR5 on B Lymphocytes during Active Graves’ Orbitopathy

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recommendations! Published in 2020 at "Current Eye Research"

DOI: 10.1080/02713683.2020.1786132

Abstract: ABSTRACT Purpose To characterize the phenotypic abnormalities of peripheral B cells in patients with Graves’ orbitopathy (GO) and explore the role of chemokine CXC ligand 13 and its receptor type 5 (CXCL13/CXCR5) in relation to… read more here.

Keywords: cxcr5; graves orbitopathy; expression; receptor ... See more keywords
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CXCL13 Is an Indicator of Germinal Center Activity and Alloantibody Formation Following Transplantation

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recommendations! Published in 2021 at "Transplantation Direct"

DOI: 10.1097/txd.0000000000001247

Abstract: Supplemental Digital Content is available in the text. Background. Donor-specific antibodies (DSA) are a recognized cause of allograft injury, yet biomarkers that indicate their development posttransplant or guide management are not available. CXCL13 (chemokine [C-X-C… read more here.

Keywords: germinal center; alloantibody formation; formation; cxcl13 ... See more keywords
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P055 CXCL13 as biomarker for histological involvement in sjogren’s syndrome

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recommendations! Published in 2019 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2018-ewrr2019.47

Abstract: Career situation of first and presenting author Post-doctoral fellow. Introduction Sjogren’s syndrome (SS) is an autoimmune condition characterised by systemic B cell activation, autoantibody production and ectopic germinal centers (GC) formation within salivary gland (SG).… read more here.

Keywords: biomarker; pathology; cxcl13; serum levels ... See more keywords
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FRI0652 SERUM CXCL13 LEVELS ARE ASSOCIATED WITH LYMPHOMA RISK AND LYMPHOMA OCCURRENCE IN PRIMARY SJöGREN’S SYNDROME

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recommendations! Published in 2019 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2019-eular.4134

Abstract: Background Primary Sjögren’s syndrome (pSS) is an autoimmune disease characterized by an increased risk for non-Hodgkin lymphoma (NHL) development. Ectopic germinal center (GC) formation in the salivary gland (SG) epithelium of pSS patients is thought… read more here.

Keywords: lymphoma; risk; cxcl13 levels; cxcl13 ... See more keywords
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Bioinformatics Analysis of Prognostic Significance and Immune Characteristics of CXC Chemokine Family in Patients with Lung Adenocarcinoma

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recommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2022/3918926

Abstract: Objective To screen CXC chemokines related to the risk of lung adenocarcinoma (LUAD) using bioinformatics and construct a CXC-based prognostic risk model to improve the diagnosis and treatment of LUAD patients. Methods The Cancer Genome… read more here.

Keywords: cxcl13; luad patients; luad; risk ... See more keywords
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CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.

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recommendations! Published in 2017 at "JCI insight"

DOI: 10.1172/jci.insight.91487

Abstract: T follicular helper cells (TFH cells) are important regulators of antigen-specific B cell responses. The B cell chemoattractant CXCL13 has recently been linked with TFH cell infiltration and improved survival in human cancer. Although human… read more here.

Keywords: cxcl13; cell; tfh cells; breast cancer ... See more keywords
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Levels of CXCL13 and sICAM-1 correlate with disease activity score in patients with rheumatoid arthritis treated with tocilizumab

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recommendations! Published in 2019 at "Advances in Rheumatology"

DOI: 10.1186/s42358-019-0097-1

Abstract: BackgroundTocilizumab (TCZ), a humanized monoclonal antibody against the interleukin-6 receptor, has been proven to be a safe and effective treatment for rheumatoid arthritis (RA). Because RA is a heterogenous disease and patient response to treatments… read more here.

Keywords: response; disease; cxcl13 sicam; cxcl13 ... See more keywords