CXCL2 acts as a prognostic biomarker and associated with immune infiltrates in stomach adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031096
Abstract: Background: STAD ranked 5th most common in the incidence of malignant tumors and 3rd most common in the death rate of cancer worldwide. CXC chemokines affect the biological progress of various tumors, resulting in therapeutic… read more here.
Keywords: acts prognostic; cxcl2 level; associated immune; cxcl2 acts ... See more keywords
NFATc3 Promotes Pulmonary Inflammation and Fibrosis by Regulating Production of CCL2 and CXCL2 in Macrophage.
Sign Up to like & getrecommendations! Published in 2023 at "Aging and disease"
DOI: 10.14336/ad.2022.1202
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive and highly lethal inflammatory interstitial lung disease characterized by aberrant extracellular matrix deposition. Macrophage activation by cytokines released from repetitively injured alveolar epithelial cells regulates the inflammatory response,… read more here.
Keywords: blm; ccl2 cxcl2; fibrosis; macrophage ... See more keywords
Ursolic Acid Ameliorates the Injury of H9c2 Cells Caused by Hypoxia and Reoxygenation Through Mediating CXCL2/NF-κB Pathway.
Sign Up to like & getrecommendations! Published in 2022 at "International heart journal"
DOI: 10.1536/ihj.21-807
Abstract: Ursolic acid (UA) has been reported to possess several biological benefits, such as anti-cancer, anti-inflammation, antibacterial, and neuroprotective functions. This study detects the function and molecular mechanism of UA in H9c2 cells under hypoxia and… read more here.
Keywords: hypoxia reoxygenation; h9c2 cells; induced h9c2; ursolic acid ... See more keywords
Application of genomic selection and experimental techniques to predict cell death and immunotherapeutic efficacy of ferroptosis-related CXCL2 in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.998736
Abstract: Since most hepatocellular carcinoma (HCC) patients are diagnosed at advanced stages, there is no effective treatment to improve patient survival. Ferroptosis, a regulated cell death driven by iron accumulation and lipid peroxidation, has been reported… read more here.
Keywords: cell death; cell; hcc; ferroptosis related ... See more keywords
Combining TMZ and SB225002 induces changes of CXCR2 and VEGFR signalling in primary human endothelial cells in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Reports"
DOI: 10.3892/or.2022.8373
Abstract: Standard of care therapy for glioblastoma (GBM) consisting of surgical removal, temozolomide (TMZ) and radiotherapy fails to cure the disease and median survival is limited to 15 months. Therapeutic approaches targeting vascular endothelial growth factor… read more here.
Keywords: endothelial cells; il8; expression; cxcr2 ... See more keywords
Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "BMB Reports"
DOI: 10.5483/bmbrep.2018.51.12.140
Abstract: C-X-C motif chemokine ligand 2 (CXCL2) is a small secreted protein that exhibits a structure similar to the proangiogenic subgroup of the CXC chemokine family. Recently, accumulating evidence suggests that chemokines play a pivotal role… read more here.
Keywords: hepatocellular carcinoma; cell proliferation; cxcl2; hcc ... See more keywords
SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.66854
Abstract: Background: There is increasing evidence that tumour-associated macrophages (TAMs) are critical in the formation of lung metastases. However, the molecular mechanisms of tumour interactions with TAMs via EMT are largely unknown. Methods: The mechanism of… read more here.
Keywords: metastasis; lung metastasis; snail; colorectal cancer ... See more keywords