PTH1R translocation to primary cilia in mechanically‐stimulated ostecytes prevents osteoclast formation via regulation of CXCL5 and IL‐6 secretion
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30849
Abstract: Osteocytes respond to mechanical forces controlling osteoblast and osteoclast function. Mechanical stimulation decreases osteocyte apoptosis and promotes bone formation. Primary cilia have been described as potential mechanosensors in bone cells. Certain osteogenic responses induced by… read more here.
Keywords: pth1r; mechanically stimulated; cxcl5; mlo ... See more keywords
CXCL5 promotes mitomycin C resistance in non-muscle invasive bladder cancer by activating EMT and NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.071
Abstract: The emergence of chemoresistance greatly increases the recurrence risk for non-muscle invasive bladder cancer (NMIBC) patients, which is still a big concern of clinicians. Understanding the mechanisms of drug resistance is of great significance for… read more here.
Keywords: cxcl5; bladder cancer; resistance; emt pathway ... See more keywords
Association of Single Nucleotide Polymorphisms in the CXCR1, CXCR2 and CXCL5 with the Behçet's Disease in Denizli Province of Turkey.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and experimental dermatology"
DOI: 10.1111/ced.14766
Abstract: BACKGROUND Behçet's disease (BD) is associated with the immune system, especially neutrophilic activity. The CXCR1, CXCR2 and CXCL5 mediate the activation and migration of the neutrophils. OBJECTIVES The aim of our study was to investigate… read more here.
Keywords: cxcr2 cxcl5; cxcr1 cxcr2; disease; cxcl5 ... See more keywords
Prognostic significance of CXCL5 expression in cancer patients: a meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cell International"
DOI: 10.1186/s12935-018-0562-7
Abstract: BackgroundCXCL5 is a member of the CXC-type chemokine family, which has been found to play important roles in tumorigenesis and cancer progression. Recent studies have demonstrated that CXCL5 could serve as a potential prognostic biomarker… read more here.
Keywords: cxcl5 expression; cxcl5; cancer; cancer patients ... See more keywords
CXCL5 expression in tumor tissues is associated with poor prognosis in patients with pancreatic cancer
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.12120
Abstract: Immunotherapy based on the tumor microenvironment is a feasible method for treating cancer; therefore, it is necessary to investigate the immune microenvironment of pancreatic cancer and the influencing factors of the immune microenvironment. Chemokines are… read more here.
Keywords: prognosis; pancreatic cancer; cxcl5; expression ... See more keywords