Articles with "cxcl6" as a keyword



CXCL6 is an important paracrine factor in the pro-angiogenic human cardiac progenitor-like cell secretome

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-11976-6

Abstract: Studies in recent years have established that the principal effects in cardiac cell therapy are associated with paracrine/autocrine factors. We combined several complementary techniques to define human cardiac progenitor cell (CPC) secretome constituted by 914… read more here.

Keywords: cxcl6; cpc; cxcl6 important; cardiac progenitor ... See more keywords

Ethanol promoting the upregulation of C-X-C Motif Chemokine Ligand 1(CXCL1) and C-X-C Motif Chemokine Ligand 6(CXCL6) in models of early alcoholic liver disease

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2030557

Abstract: ABSTRACT Alcoholic liver disease (ALD) denotes a series of liver diseases caused by ethanol. Recently, immune-related genes (IRGs) play increasingly crucial role in diseases. However, it’s unclear the role of IRGs in ALD. Bioinformatic analysis… read more here.

Keywords: motif chemokine; chemokine ligand; cxcl6; cxcl1 cxcl6 ... See more keywords

P1193 Cross-Disease Analysis Unveils CXCL6 as a Shared Immune Mediator in Ulcerative Colitis and Periodontitis: Novel Insights from Bioinformatics

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Published in 2025 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjae190.1367

Abstract: Emerging evidence underscores a pathological bidirectional relationship between ulcerative colitis (UC) and periodontitis (PD) through the oral-gut axis, highlighting a complex interplay with significant implications for patient health. However, the shared molecular features underlying this… read more here.

Keywords: analysis; cxcl6; ulcerative colitis; colitis periodontitis ... See more keywords

Thrombomodulin and CXCL6 Altered Expression in Preeclampsia: Serum-Placental Biomarker Correlations and Clinical Significance.

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Published in 2025 at "American journal of reproductive immunology"

DOI: 10.1111/aji.70192

Abstract: We aimed to examine the expression levels of thrombomodulin (THBD) and C‐X‐C motif ligand 6 (CXCL6/GCP‐2) in the serum and placental tissues of pregnant women with preeclampsia (PE) and assess their clinical significance. read more here.

Keywords: expression; cxcl6; clinical significance; serum placental ... See more keywords

CXCL6‐EGFR‐induced Kupffer cells secrete TGF‐β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C‐MYC/EZH2 pathway in liver fibrosis

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Published in 2018 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.13787

Abstract: Liver fibrosis is the excessive accumulation of extracellular matrix proteins in response to the inflammatory response that accompanies tissue injury, which at an advanced stage can lead to cirrhosis and even liver failure. This study… read more here.

Keywords: cxcl6; fibrosis; liver fibrosis; tgf ... See more keywords

CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway

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Published in 2019 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2019.00224

Abstract: In this study the role of CXCL6 in diabetic nephropathy (DN) was investigated. It was found to be overexpression in DN patients and DN rat model. And the expression of fibrosis-related cytokines was consistent with… read more here.

Keywords: cxcl6; jak stat3; fibrosis; stat3 signaling ... See more keywords