Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signaling
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DOI: 10.1172/jci.insight.180287
Abstract: CD4+ T helper 1 (Th1) cells coordinate adaptive immune responses to intracellular pathogens, including viruses. Key to this function is the ability of Th1 cells to migrate within secondary lymphoid tissues, as well as to… read more here.
Keywords: stat1 signaling; th1; th1 cells; cxcr3 expression ... See more keywords
CXCR3 Expression and Genome-Wide 3′ Splice Site Selection in the TCGA Breast Cancer Cohort
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DOI: 10.3390/life11080746
Abstract: CXCR3 is a chemokine receptor with two well-characterized isoforms that have unique, context-dependent roles: CXCR3-A and CXCR3-B, which are produced through alternative 3′ splice site selection (A3SS). RNA-seq data from The Cancer Genome Atlas (TCGA)… read more here.
Keywords: cancer; cxcr3; cxcr3 expression; breast cancer ... See more keywords