Agonist-induced CXCR4 and CB2 Heterodimerization Inhibits Gα13/RhoA-mediated Migration
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DOI: 10.1158/1541-7786.mcr-16-0481
Abstract: G-protein–coupled receptor (GPCR) heterodimerization has emerged as a means by which alternative signaling entities can be created; yet, how receptor heterodimers affect receptor pharmacology remains unknown. Previous observations suggested a biochemical antagonism between GPCRs, CXCR4… read more here.
Keywords: migration; heterodimerization; cb2; cancer ... See more keywords