Biomimetic Nanovaccines Potentiating Dendritic Cell Internalization via CXCR4‐Mediated Macropinocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202064
Abstract: Although targeted delivery of nanoparticulate vaccines to dendritic cells (DCs) holds tremendous potential, it still faces insufficient internalization and endosome degradation via the receptor‐mediated endocytosis pathway. Inspired by the advantages of CXC‐chemokine receptor type 4… read more here.
Keywords: biomimetic nanovaccines; internalization; mediated macropinocytosis; macropinocytosis ... See more keywords
Bioinformatic analyses reveal the key pathways and genes in the CXCR4 mediated mesenchymal subtype of glioblastoma
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DOI: 10.3892/mmr.2018.9011
Abstract: Glioblastoma multiforme (GBM) is one of the most lethal types of tumour, despite severe treatment methods. The Cancer Genome Atlas has categorised GBMs into proneural, neural, classical and mesenchymal subtypes; the mesenchymal subgroup has the… read more here.
Keywords: cxcr4 mediated; mesenchymal subtype; glioblastoma; mesenchymal gbm ... See more keywords