CXCR4‐targeting nanobodies differentially inhibit CXCR4 function and HIV entry
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.10.015
Abstract: &NA; The chemokine receptor CXCR4 and its ligand CXCL12 contribute to a variety of human diseases, such as cancer. CXCR4 is also a major co‐receptor facilitating HIV entry. Accordingly, CXCR4 is considered as an attractive… read more here.
Keywords: hiv entry; cxcr4 targeting; activity; targeting nanobodies ... See more keywords
An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030655
Abstract: The chemokine receptor 4 (CXCR4) is a promising diagnostic and therapeutic target for the management of various cancers. CXCR4 has been utilized in immunotherapy, targeted drug delivery, and endoradiotherapy. Poly(amidoamine) [PAMAM] dendrimers are well-defined polymers… read more here.
Keywords: targeting pamam; evaluation cxcr4; cxcr4; pamam dendrimer ... See more keywords