Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3’,5’-Monophosphate-Dependent Protein Kinase I
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DOI: 10.1161/hypertensionaha.122.18756
Abstract: Background: We previously demonstrated that nitroxyl causes vasodilation, at least in part, by inducing the formation of an intradisulfide bond between C117 and C195 in the high affinity cyclic guanosine monophosphate-binding site of PKGI (cyclic… read more here.
Keywords: guanosine monophosphate; blood pressure; pressure; cyclic guanosine ... See more keywords