LyP-1 Conjugated Nanoparticles for Magnetic Resonance Imaging of Triple Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-017-1140-4
Abstract: PurposeTriple-negative breast cancer (TNBC) does not express estrogen receptor, progesterone receptor, or Her2/neu. Both diagnosis and treatment of TNBC remain a clinical challenge. LyP-1 is a cyclic 9 amino acid peptide that can bind to… read more here.
Keywords: lyp fe3o4; fe3o4 cy5; breast; cy5 ... See more keywords
Facile preparation of near-infrared fluorescence and magnetic resonance dual-modality imaging probes based on mesoporous organosilica nanoparticles.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.12.067
Abstract: In this work, near-infrared fluorescence (NIRF) and magnetic resonance (MR) dual-modality imaging probes are prepared by conjugating maleimide derivative cyanine dye (Mal-Cy5.5), gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA), and RGD peptide (Mal-PEG2-RGD) on thioether-bridged mesoporous organosilica nanoparticles… read more here.
Keywords: resonance dual; cy5; near infrared; magnetic resonance ... See more keywords
Squalene-PEG-Exendin as High-Affinity Constructs for Pancreatic Beta-Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00186
Abstract: Novel drug delivery systems targeting native, transplanted, or cancerous beta-cells are of utmost importance. Herein, we present new exendin-4 derivatives with modified unnatural amino acids at strategic positions within the polypeptide sequence. The modified peptides… read more here.
Keywords: beta cells; affinity; cy5; beta ... See more keywords
Synthesis of Substituted Cy5 Phosphoramidite Derivatives and Their Incorporation into Oligonucleotides Using Automated DNA Synthesis
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06921
Abstract: Cyanine dyes represent a family of organic fluorophores with widespread utility in biological-based applications ranging from real-time PCR probes to protein labeling. One burgeoning use currently being explored with indodicarbocyanine (Cy5) in particular is that… read more here.
Keywords: dna; synthesis; dna synthesis; incorporation ... See more keywords
Preparation of poly-l-lysine-based nanoparticles with pH-sensitive release of curcumin for targeted imaging and therapy of liver cancer in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Drug Delivery"
DOI: 10.1080/10717544.2018.1461957
Abstract: Abstract Poly-l-lysine (PLL) nanoparticle (NP) system was prepared for the controlled release of curcumin (CUR) by pH stimuli, and its theranostic efficacy on cancer was compared to that of CUR solution in vitro and in… read more here.
Keywords: poly lysine; vitro vivo; cy5; release curcumin ... See more keywords