Screening of an annexin‐A2‐targeted heptapeptide for pancreatic adenocarcinoma localization
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13352
Abstract: Annexin A2 (ANXA2) encodes an oncoprotein whose expression has been found to correlate with poorer overall survival (OS) of pancreatic adenocarcinoma (PAAD) patients. Although peptides are available for targeting ANXA2, none of these were initially… read more here.
Keywords: pancreatic adenocarcinoma; cy7; screening annexin; cy7 yw7 ... See more keywords
Assembly of multifunction dyes and heat shock protein 90 inhibitor coupled to bovine serum albumin in nanoparticles for multimodal photodynamic/photothermal/chemo-therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2021.01.052
Abstract: The proangiogenic protein, survivin, is a client protein for heat shock protein 90 (Hsp-90), whose overexpression is induced by photodynamic therapy (PDT), leading to the inhibition of capase-9 and the blockage of apoptosis. The overexpression… read more here.
Keywords: protein; cy7; heat shock; shock protein ... See more keywords
A Gold Nanocage Probe Targeting Survivin for the Diagnosis of Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051547
Abstract: In this paper, Au nanocages (AuNCs) loaded with the MRI contrast agent gadolinium (Gd) and capped with the tumor-targeting gene survivin (Sur–AuNC•Gd–Cy7 nanoprobes) were designed and applied as a targeted imaging agent for pancreatic cancer.… read more here.
Keywords: cy7; sur aunc; pancreatic cancer; aunc cy7 ... See more keywords