Paired Electrolysis for Decarboxylative Cyanation: 4-CN-Pyridine, a Versatile Nitrile Source.
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DOI: 10.1021/acs.orglett.2c01897
Abstract: A decarboxylative cyanation of amino acids under paired electrochemical reaction conditions has been developed. 4-CN-pyridine was found to be a new and effective cyanation reagent under catalyst-free conditions. Mechanistic studies support a nucleophilic reaction pathway,… read more here.
Keywords: cyanation pyridine; cyanation; paired electrolysis; decarboxylative cyanation ... See more keywords