Silver-Mediated Direct C-H Cyanation of Terminal Alkynes with N-Isocyanoiminotriphenylphosphorane.
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DOI: 10.1021/acs.orglett.7b02743
Abstract: A direct cyanation of terminal alkynes for the synthesis of propionitrile derivatives, with the aid of silver salt using water additive, has been achieved. The cyano source used is N-isocyanoiminotriphenylphosphorane, which is nontoxic, safe, and… read more here.
Keywords: cyanation terminal; silver mediated; terminal alkynes; direct cyanation ... See more keywords