Regioselective α-Cyanation of Unprotected Alicyclic Amines.
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DOI: 10.1021/acs.orglett.2c02148
Abstract: Secondary alicyclic amines are converted to α-aminonitriles via addition of TMSCN to their corresponding imines, intermediates that are produced in situ via the oxidation of amine-derived lithium amides with simple ketone oxidants. Amines with an… read more here.
Keywords: unprotected alicyclic; cyanation; cyanation unprotected; regioselective cyanation ... See more keywords