Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group
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DOI: 10.1021/acsomega.2c01399
Abstract: The reactivity of the diaminomaleonitrile-based imines containing hydroxyphenyl substituents with diverse aromatic aldehydes has been explored for the synthesis of novel highly substituted nitrogen heterocycles, which are considered privileged scaffolds in drug discovery. We report… read more here.
Keywords: cyano hydroxyaryl; hydroxyaryl imidazole; synthesis; group ... See more keywords