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Published in 2023 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202300067
Abstract: The discovery of new therapeutic drugs is heavily reliant on the structural diversity and pharmacological properties of heterocyclic compounds. Pyridine heterocyclic-related medicines, in particular, have garnered considerable attention due to their wide pharmacological activities and…
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Keywords:
activities novel;
review biological;
cyanopyridine derivatives;
novel cyanopyridine ... See more keywords
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Published in 2018 at "Catalysis Letters"
DOI: 10.1007/s10562-018-2318-3
Abstract: An efficient and convenient method was investigated for synthesis of 2-amino-3-cyanopyridine derivatives via a one-pot four-component reaction of various types of aldehydes, acetophenone, malononitrile, and ammonium acetate in the presence of 10 mg Cu@imineZCMNPs catalyst. The…
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Keywords:
four component;
microscopy;
synthesis amino;
amino cyanopyridine ... See more keywords
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Published in 2020 at "Mendeleev Communications"
DOI: 10.1016/j.mencom.2020.07.031
Abstract: New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the Gram-positive B. subtilis was tested,…
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Keywords:
amino;
activity amino;
antibacterial activity;
amino cyanopyridine ... See more keywords
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Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1616096
Abstract: Abstract New pyridine derivatives bearing p-dimethyl amino phenyl and p-bromophenyl moieties at position-4 and 6 have been prepared. The behavior of pyridone derivative 2 toward ethyl chloroacetate followed by hydrazine hydrate gave pyridinyl acetohydrazide derivative…
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Keywords:
novel cyanopyridine;
assessment novel;
synthesis biological;
cyanopyridine derivatives ... See more keywords