Discovery of 2-Amino-3-cyanothiophene Derivatives as Potent STAT3 Inhibitors for the Treatment of Osteosarcoma Growth and Metastasis.
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DOI: 10.1021/acs.jmedchem.2c00004
Abstract: Osteosarcoma is one of the most common malignant bone tumors. However, the treatment and clinical outcomes of osteosarcoma have hardly changed over the past three decades due to the comprehensive heterogeneity and higher rate of… read more here.
Keywords: metastasis; cyanothiophene derivatives; growth metastasis; treatment ... See more keywords