P13.11 Transcriptional CDK inhibitors, CYC065 and THZ1 promote apoptosis in preclinical models of primary and recurrent GBM tumour cells and glioma stem cells
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DOI: 10.1093/neuonc/noab180.119
Abstract: Activation of cyclin-dependent kinases (CDKs) contributes to the uncontrolled proliferation of tumour cells. Genomic alterations that lead to the constitutive activation of CDKs are a feature of many tumours including glioblastoma (GBM), the most common… read more here.
Keywords: primary recurrent; cdk inhibitors; apoptosis; gbm ... See more keywords