Articles with "cyclase diseases" as a keyword



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Glutaminyl Cyclase, Diseases, and Development of Glutaminyl Cyclase Inhibitors.

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Published in 2021 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.1c00325

Abstract: Pyroglutamate (pE) modification, catalyzed mainly by glutaminyl cyclase (QC), is prevalent throughout nature and is particularly important in mammals including humans for the maturation of hormones, peptides, and proteins. In humans, the upregulation of QC… read more here.

Keywords: glutaminyl cyclase; diseases development; cyclase diseases; cyclase ... See more keywords