Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential
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DOI: 10.3389/fphys.2022.1013845
Abstract: In mammalian cells, 10 different adenylyl cyclases produce the ubiquitous second messenger, cyclic adenosine monophosphate (cAMP). Amongst these cAMP-generating enzymes, bicarbonate (HCO3 −)-regulated soluble adenylyl cyclase (sAC; ADCY10) is uniquely essential in sperm for reproduction.… read more here.
Keywords: binding kinetics; sac; cyclase sac; adenylyl cyclase ... See more keywords