Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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DOI: 10.1016/j.cell.2018.07.019
Abstract: The urea cycle (UC) is the main pathway by which mammals dispose of waste nitrogen. We find that specific alterations in the expression of most UC enzymes occur in many tumors, leading to a general… read more here.
Keywords: dysregulation generates; cycle dysregulation; generates clinically; cycle ... See more keywords
Cell-Cycle Dysregulation in the Pathogenesis of Diabetic Kidney Disease: An Update
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032133
Abstract: In the last few decades, the prevalence of diabetes mellitus (DM) has increased rapidly. Diabetic kidney disease (DKD) is the major cause of end-stage renal disease (ESRD) globally, attributed to hemodynamic changes and chronic hyperglycemia.… read more here.
Keywords: disease; cycle; cell cycle; cycle dysregulation ... See more keywords