Daughter-cell-specific modulation of nuclear pore complexes controls cell cycle entry during asymmetric division
Sign Up to like & getrecommendations! Published in 2018 at "Nature cell biology"
DOI: 10.1038/s41556-018-0056-9
Abstract: The acquisition of cellular identity is coupled to changes in the nuclear periphery and nuclear pore complexes (NPCs). Whether and how these changes determine cell fate remain unclear. We have uncovered a mechanism that regulates… read more here.
Keywords: cell; cycle entry; daughter cell; cell cycle ... See more keywords
Hippo signaling and histone methylation control cardiomyocyte cell cycle re-entry through distinct transcriptional pathways
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281610
Abstract: Aims Accumulating data demonstrates that new adult cardiomyocytes (CMs) are generated throughout life from pre-existing CMs, although the absolute magnitude of CM self-renewal is very low. Modifying epigenetic histone modifications or activating the Hippo-Yap pathway… read more here.
Keywords: cycle entry; cell; cell cycle; hippo ... See more keywords
Cell Cycle Re-entry in the Nervous System: From Polyploidy to Neurodegeneration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.698661
Abstract: Terminally differentiated cells of the nervous system have long been considered to be in a stable non-cycling state and are often considered to be permanently in G0. Exit from the cell cycle during development is… read more here.
Keywords: nervous system; cell; cycle entry; cell cycle ... See more keywords
Molecular mechanism of acetylsalicylic acid in improving learning and memory impairment in APP/PS1 transgenic mice by inhibiting the abnormal cell cycle re-entry of neurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1006216
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disorder accompanied by the loss and apoptosis of neurons. Neurons abnormally enter the cell cycle, which results in neuronal apoptosis during the course of AD development and progression. However,… read more here.
Keywords: cycle entry; cell cycle; app ps1; mice ... See more keywords