The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
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DOI: 10.1158/2159-8290.cd-19-0970
Abstract: Deciphering the impact of metabolic intervention on response to anticancer therapy may elucidate a path toward improved clinical responses. Here, we identify amino acid-related pathways connected to the folate cycle whose activation predicts sensitivity to… read more here.
Keywords: cycle; folate cycle; cycle enzyme; targeting therapies ... See more keywords