Production of single‐cycle infectious SARS‐CoV‐2 through a trans‐complemented replicon
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DOI: 10.1002/jmv.28057
Abstract: Single‐cycle infectious virus can elicit close‐to‐natural immune response and memory. One approach to generate single‐cycle severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is through deletion of structural genes such as spike (S) and nucleocapsid (N). Transcomplementation… read more here.
Keywords: cycle; cycle infectious; expression; single cycle ... See more keywords